[Comparison of the immunological indices of the peripheral blood and lymph nodes in lymphogranulomatosis in children].

The paper deals with the evaluation of immunologic vigor in 57 cases of pediatric Hodgkin's disease. The study used the standard test of spontaneous rosette formation of lymphocytes of peripheral blood and lymph nodes with sheep erythrocytes and some modifications of the said procedure. Patients with Hodgkin's disease and healthy subjects revealed similar levels of main subpopulations of circulating T-lymphocytes. This was matched by a shift in the ratio of T-cell subpopulations toward predominant theophylline-resistant ones (T-helpers) in the lymph nodes of patients with Hodgkin's disease.