Department of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Oklahoma Tobacco Research Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
Psychophysiology. 2019 Apr;56(4):e13309. doi: 10.1111/psyp.13309. Epub 2018 Dec 16.
While some individuals can defy the lure of temptation, many others find appetizing food irresistible. The goal of this study was to investigate the neuropsychological mechanisms that increase individuals' vulnerability to cue-induced eating. Using ERPs, a direct measure of brain activity, we showed that individuals with larger late positive potentials in response to food-related cues than to erotic images are more susceptible to cue-induced eating and, in the presence of a palatable food option, eat more than twice as much as individuals with the opposite brain reactivity profile. By highlighting the presence of individual brain reactivity profiles associated with susceptibility to cue-induced eating, these findings contribute to the understanding of the neurobiological basis of vulnerability to obesity.
虽然有些人能够抵制诱惑,但也有许多人觉得美味的食物难以抗拒。本研究旨在探究增加个体对线索诱导进食易感性的神经心理学机制。通过使用事件相关电位(ERP)这一直接测量大脑活动的方法,我们发现,与性图像相比,对食物线索反应有更大的晚期正电位的个体更容易受到线索诱导进食的影响,而且在存在美味食物选择的情况下,他们的进食量是具有相反大脑反应特征个体的两倍多。这些发现通过突出与线索诱导进食易感性相关的个体大脑反应特征的存在,为理解肥胖易感性的神经生物学基础做出了贡献。