Li Shuxiang, Wang Kun, Sun Han, Luo Xiaomin, Wang Peng, Fang Sheng, Chen Haifeng, Sun Xiaoliang
Articular Orthopaedics, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Medicine (Baltimore). 2018 Dec;97(50):e13687. doi: 10.1097/MD.0000000000013687.
The argument on whether extracorporeal shock-wave therapy (ESWT) and corticosteroid injections (CSIs) exert an equivalent pain control or which is the better treatment for plantar fasciitis (PF) in adults remains to be resolved. It is important and necessary to conduct a meta-analysis to make a relatively more credible and overall assessment about which treatment method performs better pain control in treatment of PF in adults.
From the inception to July 2018, the Embase, PubMed, Web of Science, and Cochrane Library electronic databases were searched for all relevant studies. Only randomized controlled trials (RCTs) focusing on comparing ESWT and CSI therapies in PF cases in adults were included. The primary outcome measure was visual analog scale (VAS) reduction, whereas the secondary outcomes included treatment success rate, recurrence rate, function scores, and adverse events.
Nine RCTs involving 658 cases were included in this meta-analysis. In the present study, meta-analysis showed that high-intensity ESWT had superior pain relief and success rates relative to the CSI group within 3 months, but the ESWT with low intensity was slightly inferior to CSI for efficacy within 3 months. In addition, patients with CSI may tend to increase the need for the analgesic and more adverse events may be associated with the ESWT. However, the ESWT and CSI present similar recurrent rate and functional outcomes.
Our analysis showed that the pain relief and success rates were related to energy intensity levels, with the high-intensity ESWT had the highest probability of being the best treatment within 3 months, followed by CSI, and low-intensity ESWT. More high-quality RCTs with long-term follow-up time are needed to further compare the differences of CSI and ESWT for adults with PF.
关于体外冲击波疗法(ESWT)和皮质类固醇注射(CSI)在成人足底筋膜炎(PF)治疗中是否能实现同等程度的疼痛控制,或者哪种疗法更佳,这一争论仍有待解决。开展一项荟萃分析,以便对哪种治疗方法在成人PF治疗中能实现更好的疼痛控制做出相对更可靠、更全面的评估,这一点至关重要且很有必要。
从建库至2018年7月,检索了Embase、PubMed、Web of Science和Cochrane图书馆电子数据库中的所有相关研究。仅纳入聚焦于比较成人PF病例中ESWT和CSI疗法的随机对照试验(RCT)。主要结局指标为视觉模拟量表(VAS)评分降低情况,次要结局包括治疗成功率、复发率、功能评分和不良事件。
本荟萃分析纳入了9项涉及658例病例的RCT。在本研究中,荟萃分析表明,高强度ESWT在3个月内相对于CSI组具有更好的疼痛缓解效果和成功率,但低强度ESWT在3个月内的疗效略逊于CSI。此外,接受CSI治疗的患者可能更倾向于增加镇痛药物的使用,且ESWT可能会伴随更多不良事件。然而,ESWT和CSI的复发率和功能结局相似。
我们的分析表明,疼痛缓解效果和成功率与能量强度水平相关,高强度ESWT在3个月内成为最佳治疗方法的可能性最高,其次是CSI,低强度ESWT最低。需要更多长期随访的高质量RCT来进一步比较CSI和ESWT在成人PF治疗中的差异。