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糖皮质激素注射与非侵入性治疗足底筋膜炎的疗效比较:系统评价和荟萃分析。

Comparative efficacy of corticosteroid injection and non-invasive treatments for plantar fasciitis: a systematic review and meta-analysis.

机构信息

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Chiayi, Taiwan.

School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.

出版信息

Sci Rep. 2018 Mar 5;8(1):4033. doi: 10.1038/s41598-018-22402-w.

DOI:10.1038/s41598-018-22402-w
PMID:29507320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5838257/
Abstract

The first choice of treatment for patients with plantar fasciitis is non-invasive treatment, rather than corticosteroid injection (CSI). However, no comprehensive study has compared the effectiveness of CSI with non-invasive treatments for plantar fasciitis. We conducted a meta-analysis comparing CSI and non-invasive treatment effects on plantar fasciitis. The primary outcome was pain reduction. Nine randomized controlled trials comparing CSI with 4 non-invasive treatment types were included. A trend favoring CSI over non-invasive treatments was indicated regarding reduction in the visual analogue scale (VAS) score at 1-1.5 (mean difference (MD), 1.70; 95% confidence interval (CI) = 0.39-3.01; P = 0.01) and 2-3 months (MD, 1.67; 95% CI = 0.58-2.76; P = 0.003). At 1.5-month follow-up, CSI was associated with improved VAS score compared with physical therapy (PT) (MD, 2.5; 95% CI = 0.1-4.9; P = 0.04). No significant differences in the VAS score reduction were observed between CSI and shock wave therapy within 3 months. In summary, CSI tends to be more effective for pain reduction than non-invasive treatments within 3 months. Moreover, CSI provides significant pain relief at 1.5 months after treatment compared with PT. This study provides important clinical information for selecting therapeutics.

摘要

足底筋膜炎患者的首选治疗方法是非侵入性治疗,而不是皮质类固醇注射(CSI)。然而,目前还没有综合研究比较 CSI 与非侵入性治疗足底筋膜炎的效果。我们进行了一项荟萃分析,比较 CSI 与非侵入性治疗足底筋膜炎的效果。主要结局是疼痛减轻。共纳入 9 项比较 CSI 与 4 种非侵入性治疗类型的随机对照试验。结果显示 CSI 在减轻视觉模拟量表(VAS)评分方面优于非侵入性治疗,1-1.5 个月(MD,1.70;95%置信区间(CI)=0.39-3.01;P=0.01)和 2-3 个月(MD,1.67;95% CI=0.58-2.76;P=0.003)时更明显。在 1.5 个月随访时,CSI 与物理治疗(PT)相比,VAS 评分改善(MD,2.5;95% CI=0.1-4.9;P=0.04)。在 3 个月内,CSI 与冲击波治疗在减轻 VAS 评分方面无显著差异。总之,CSI 在 3 个月内对疼痛缓解的效果优于非侵入性治疗。此外,CSI 在治疗后 1.5 个月时与 PT 相比,能提供显著的疼痛缓解。本研究为治疗选择提供了重要的临床信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/605e/5838257/0710a614393a/41598_2018_22402_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/605e/5838257/526e0fc5f039/41598_2018_22402_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/605e/5838257/0710a614393a/41598_2018_22402_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/605e/5838257/526e0fc5f039/41598_2018_22402_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/605e/5838257/0710a614393a/41598_2018_22402_Fig2_HTML.jpg

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