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Reply to Gronwald et al.: Exercise intensity does indeed matter; maximal oxygen uptake is the gold-standard indicator.回复格伦瓦尔德等人：运动强度确实很重要；最大摄氧量是金标准指标。
Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E11892-E11893. doi: 10.1073/pnas.1818247115.
2
Forearm oxygen uptake during maximal forearm dynamic exercise.最大前臂动态运动期间的前臂摄氧量。
Eur J Appl Physiol Occup Physiol. 1989;58(5):466-70. doi: 10.1007/BF02330698.
3
Predicting maximal oxygen uptake from the 6 min walk test in patients with heart failure.通过6分钟步行试验预测心力衰竭患者的最大摄氧量。
ESC Heart Fail. 2021 Feb;8(1):47-54. doi: 10.1002/ehf2.13167. Epub 2020 Dec 10.
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Blood flow regulation and oxygen uptake during high-intensity forearm exercise.高强度前臂运动期间的血流调节与氧气摄取
J Appl Physiol (1985). 2017 Apr 1;122(4):907-917. doi: 10.1152/japplphysiol.00983.2016. Epub 2017 Jan 5.
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Oxygen Uptake at Critical Speed and Power in Running: Perspectives and Practical Applications.临界速度和功率下跑步中的摄氧量：观点与实际应用。
Int J Sports Physiol Perform. 2022 Mar 1;17(3):400-406. doi: 10.1123/ijspp.2021-0207. Epub 2021 Dec 15.
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Submaximal spiroergometric parameters are unaffected by severity of chronic obstructive pulmonary diseases.次最大量运动肺功能参数不受慢性阻塞性肺疾病严重程度的影响。
In Vivo. 2013 Nov-Dec;27(6):835-42.
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Acute administration of high doses of taurine does not substantially improve high-intensity running performance and the effect on maximal accumulated oxygen deficit is unclear.急性给予高剂量牛磺酸并不能显著改善高强度跑步表现，且其对最大累积氧亏的影响尚不清楚。
Appl Physiol Nutr Metab. 2016 May;41(5):498-503. doi: 10.1139/apnm-2015-0435. Epub 2016 Jan 8.
8
Exercise modality effect on oxygen uptake off-transient kinetics at maximal oxygen uptake intensity.运动方式对最大摄氧量强度下摄氧量非瞬态动力学的影响。
Exp Physiol. 2015 Jun;100(6):719-29. doi: 10.1113/EP085014. Epub 2015 May 20.
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Cardiorespiratory fitness data from 18,189 participants who underwent treadmill cardiopulmonary exercise testing in a Brazilian population.来自巴西人群中 18189 名接受跑步机心肺运动测试的参与者的心肺适应性数据。
PLoS One. 2019 Jan 9;14(1):e0209897. doi: 10.1371/journal.pone.0209897. eCollection 2019.
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Long-lasting exercise involvement protects against decline in O and O kinetics in moderately active women.长期的运动参与可防止适度活跃女性的 O 和 O 动力学下降。
Appl Physiol Nutr Metab. 2021 Feb;46(2):108-116. doi: 10.1139/apnm-2020-0307. Epub 2020 Jul 8.

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Exercise Benefits Dentate Gyrus Function: Bridging from Animal Models to Human High-Resolution Functional MRI of Pattern Separation.运动有益于齿状回功能：从动物模型到人类模式分离的高分辨率功能磁共振成像的桥梁。
Adv Neurobiol. 2025;44:95-111. doi: 10.1007/978-981-95-0066-6_5.
2
Causes and Consequences of Interindividual Response Variability: A Call to Apply a More Rigorous Research Design in Acute Exercise-Cognition Studies.个体间反应变异性的原因与后果：呼吁在急性运动-认知研究中应用更严谨的研究设计。
Front Physiol. 2021 Jul 22;12:682891. doi: 10.3389/fphys.2021.682891. eCollection 2021.
3
A Discussion on Different Approaches for Prescribing Physical Interventions - Four Roads Lead to Rome, but Which One Should We Choose?关于开具物理干预措施的不同方法的讨论——条条大路通罗马，但我们该选哪一条？
J Pers Med. 2020 Jun 27;10(3):55. doi: 10.3390/jpm10030055.
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New Directions in Exercise Prescription: Is There a Role for Brain-Derived Parameters Obtained by Functional Near-Infrared Spectroscopy?运动处方的新方向：通过功能近红外光谱获得的脑源性参数有作用吗？
Brain Sci. 2020 Jun 3;10(6):342. doi: 10.3390/brainsci10060342.
5
Dose-Response Matters! - A Perspective on the Exercise Prescription in Exercise-Cognition Research.剂量反应很重要！——运动认知研究中运动处方的一个视角
Front Psychol. 2019 Nov 1;10:2338. doi: 10.3389/fpsyg.2019.02338. eCollection 2019.

本文引用的文献

1
Increasing exercise's effect on mental health: Exercise intensity does matter.增强运动对心理健康的影响：运动强度确实重要。
Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E11890-E11891. doi: 10.1073/pnas.1818161115.
2
Rapid stimulation of human dentate gyrus function with acute mild exercise.急性轻度运动可快速刺激人齿状回功能。
Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10487-10492. doi: 10.1073/pnas.1805668115. Epub 2018 Sep 24.
3
Acute moderate exercise improves mnemonic discrimination in young adults.急性适度运动可改善年轻人的记忆辨别能力。
Hippocampus. 2017 Mar;27(3):229-234. doi: 10.1002/hipo.22695. Epub 2017 Jan 31.
4
Stress Effects on Neuronal Structure: Hippocampus, Amygdala, and Prefrontal Cortex.应激对神经元结构的影响：海马体、杏仁核与前额叶皮质
Neuropsychopharmacology. 2016 Jan;41(1):3-23. doi: 10.1038/npp.2015.171. Epub 2015 Jun 16.
5
Positive effect of acute mild exercise on executive function via arousal-related prefrontal activations: an fNIRS study.急性轻度运动通过与觉醒相关的前额叶激活对执行功能的积极影响：一项近红外光谱研究。
Neuroimage. 2014 Sep;98:336-45. doi: 10.1016/j.neuroimage.2014.04.067. Epub 2014 May 2.
6
Mild exercise increases dihydrotestosterone in hippocampus providing evidence for androgenic mediation of neurogenesis.适度运动增加海马体内的二氢睾酮，为雄激素介导神经发生提供证据。
Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):13100-5. doi: 10.1073/pnas.1210023109. Epub 2012 Jul 17.
7
Acute moderate exercise elicits increased dorsolateral prefrontal activation and improves cognitive performance with Stroop test.急性中度运动可引起背外侧前额叶激活增加，并改善 Stroop 测试的认知表现。
Neuroimage. 2010 May 1;50(4):1702-10. doi: 10.1016/j.neuroimage.2009.12.023. Epub 2009 Dec 16.
8
BDNF induction with mild exercise in the rat hippocampus.轻度运动对大鼠海马体脑源性神经营养因子的诱导作用
Biochem Biophys Res Commun. 2007 Jul 13;358(4):961-7. doi: 10.1016/j.bbrc.2007.04.173. Epub 2007 May 7.
9
A comparison of maximum oxygen uptake determination by bicycle ergometry at various pedaling frequencies and by treadmill running at various speeds.
Eur J Appl Physiol Occup Physiol. 1976 Aug 12;35(3):191-200. doi: 10.1007/BF02336193.

Reply to Gronwald et al.: Exercise intensity does indeed matter; maximal oxygen uptake is the gold-standard indicator.

作者信息

Suwabe Kazuya, Byun Kyeongho, Hyodo Kazuki, Reagh Zachariah M, Roberts Jared M, Matsushita Akira, Saotome Kousaku, Ochi Genta, Fukuie Takemune, Suzuki Kenji, Sankai Yoshiyuki, Yassa Michael A, Soya Hideaki

机构信息

Laboratory of Exercise Biochemistry and Neuroendocrinology, Faculty of Health and Sport Sciences, University of Tsukuba, 305-8574 Ibaraki, Japan.

Sports Neuroscience Division, Advanced Research Initiative for Human High Performance (ARIHHP), Faculty of Health and Sport Sciences, University of Tsukuba, 305-8574 Ibaraki, Japan.

出版信息

Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E11892-E11893. doi: 10.1073/pnas.1818247115.

DOI:10.1073/pnas.1818247115
PMID:30559331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6304988/
Abstract
摘要