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哺乳动物听觉中脑的抑制性神经回路。

Inhibitory Neural Circuits in the Mammalian Auditory Midbrain.

作者信息

Ono Munenori, Ito Tetsufumi

机构信息

Department of Physiology, School of Medicine, Kanazawa Medical University, Uchinada, Japan.

Department of Anatomy, School of Medicine, Kanazawa Medical University, Uchinada, Japan.

出版信息

J Exp Neurosci. 2018 Dec 12;12:1179069518818230. doi: 10.1177/1179069518818230. eCollection 2018.

DOI:10.1177/1179069518818230
PMID:30559596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6291857/
Abstract

The auditory midbrain is the critical integration center in the auditory pathway of vertebrates. Synaptic inhibition plays a key role during information processing in the auditory midbrain, and these inhibitory neural circuits are seen in all vertebrates and are likely essential for hearing. Here, we review the structure and function of the inhibitory neural circuits of the auditory midbrain. First, we provide an overview on how these inhibitory circuits are organized within different clades of vertebrates. Next, we focus on recent findings in the mammalian auditory midbrain, the most studied of the vertebrates, and discuss how the mammalian auditory midbrain is functionally coordinated.

摘要

听觉中脑是脊椎动物听觉通路中的关键整合中心。突触抑制在听觉中脑的信息处理过程中起着关键作用,这些抑制性神经回路在所有脊椎动物中都可见,并且可能对听力至关重要。在这里,我们综述了听觉中脑抑制性神经回路的结构和功能。首先,我们概述了这些抑制性回路在不同脊椎动物类群中的组织方式。接下来,我们关注在脊椎动物中研究最多的哺乳动物听觉中脑的最新发现,并讨论哺乳动物听觉中脑是如何进行功能协调的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1fd/6291857/d739d275e7fc/10.1177_1179069518818230-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1fd/6291857/b3e17e17cabb/10.1177_1179069518818230-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1fd/6291857/40dfdd1d623e/10.1177_1179069518818230-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1fd/6291857/d739d275e7fc/10.1177_1179069518818230-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1fd/6291857/b3e17e17cabb/10.1177_1179069518818230-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1fd/6291857/40dfdd1d623e/10.1177_1179069518818230-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1fd/6291857/d739d275e7fc/10.1177_1179069518818230-fig3.jpg

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本文引用的文献

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J Comp Neurol. 2018 Dec 1;526(17):2824-2844. doi: 10.1002/cne.24529. Epub 2018 Oct 23.
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Organization of projection from brainstem auditory nuclei to the inferior colliculus of Japanese house bat (Pipistrellus abramus).脑桥听觉核团向日本家蝠(Pipistrellus abramus)下丘的投射组织。
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Neuronal Organization in the Inferior Colliculus Revisited with Cell-Type-Dependent Monosynaptic Tracing.
重新审视下丘脑中的神经元组织,使用细胞类型依赖的单突触示踪技术。
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A circuit for detection of interaural time differences in the nucleus laminaris of turtles.一种用于检测海龟层状核中双耳时间差的电路。
J Exp Biol. 2017 Nov 15;220(Pt 22):4270-4281. doi: 10.1242/jeb.164145. Epub 2017 Sep 25.
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Corelease of Inhibitory Neurotransmitters in the Mouse Auditory Midbrain.小鼠听觉中脑抑制性神经递质的共同释放
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Identified GABAergic and Glutamatergic Neurons in the Mouse Inferior Colliculus Share Similar Response Properties.在小鼠下丘中鉴定出的γ-氨基丁酸能和谷氨酸能神经元具有相似的反应特性。
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