d'Ettorre Gabriele, Criscuolo Mario, Mazzotta Mauro
Local Health Authority, Health Unit of Occupational Prevention and Protection, Brindisi, Italy.
Department of Anatomy Pathology, "Perrino" Hospital, Brindisi, Italy.
Work. 2017;56(3):397-402. doi: 10.3233/WOR-172505.
Nearly eleven years have passed since the International Agency for Research on Cancer classified Formaldehyde (FA) as a known human carcinogen (group 1), yet the safety of anatomy pathology workers who are currently exposed to FA is still a matter of concern.
The purpose of this study was to evaluate the literature to discover which topics have been focused on and what the latest developments are in managing FA indoor pollution in anatomy pathology departments. which topics have been focused on and what the latest developments in managing FA indoor pollution in anatomy pathology departments.
For the purpose of this review, we searched for publications in PubMed and Web of Science using selected keywords. The articles were reviewed and categorized into one or more of the following three categories based on subject matter: exposure levels exposure controls and alternatives.
Our search resulted in a total of 31 publications that matched our inclusion criteria. The topics discussed, in order of frequency (from highest to lowest), were: "exposure controls", "exposure levels" and "alternatives". The most frequently suggested intervention was to improve local exhaust ventilation systems to minimize FA levels in gross anatomy laboratories.
We found a lack of evidence-based improvement interventions that aimed to control exposure to FA. According to this finding, and pending a valid chemical substitute for FA, we suggest the need for more in-depth studies targeting measures to minimize exposures to FA in pathology departments.
自国际癌症研究机构将甲醛（FA）列为已知人类致癌物（第1组）以来，已经过去了近11年，但目前接触FA的解剖病理学工作者的安全仍然是一个令人担忧的问题。
本研究的目的是评估文献，以发现哪些主题受到关注，以及解剖病理学部门在管理室内FA污染方面的最新进展。
为了进行本次综述，我们使用选定的关键词在PubMed和科学网中搜索出版物。根据主题对文章进行审查，并分为以下三类中的一类或多类：接触水平、接触控制和替代方法。
我们的搜索共得到31篇符合纳入标准的出版物。讨论的主题按频率（从高到低）依次为：“接触控制”、“接触水平”和“替代方法”。最常建议的干预措施是改进局部排风通风系统，以尽量降低大体解剖实验室中的FA水平。
我们发现缺乏旨在控制FA接触的循证改进干预措施。根据这一发现，在找到有效的FA化学替代品之前，我们建议需要针对降低病理学部门FA接触的措施进行更深入的研究。
