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美国印第安/阿拉斯加原住民母亲的出生体重与产妇年龄:对衰老假说的检验。

Birth weight and maternal age among American Indian/Alaska Native mothers: A test of the weathering hypothesis.

作者信息

Dennis Jeff A

机构信息

Dept. of Public Health, Texas Tech University Health Sciences Center, 3601 4th St., MS 9430, Lubbock, TX 79430, USA.

出版信息

SSM Popul Health. 2018 Oct 18;7:004-4. doi: 10.1016/j.ssmph.2018.10.004. eCollection 2019 Apr.

DOI:10.1016/j.ssmph.2018.10.004
PMID:30560195
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6289957/
Abstract

Substantial research has examined birth outcomes by race/ethnicity, noting not only disparities by race/ethnicity, but different maternal age patterns in low birth weight (LBW) prevalence. Few studies have examined these disparities among American Indian/Alaska Native (AI/AN) mothers, whose LBW prevalence is below the national average, despite substantial socioeconomic disadvantage among the population. Prior work has hypothesized that AI/AN mothers should exhibit LBW age patterns similar to those seen in NH black mothers as a result of exposure to cumulative stress, trauma, and socioeconomic disadvantage, but this has not been empirically tested. This paper uses data from the 2014-2016 U.S. Birth File, which contains records of all U.S. births for those years to examine maternal age patterns in birth weight among AI/AN mothers. Importantly, this study also considers high birth weight (HBW) births, given higher prevalence of diabetes in the AI/AN population, and proposes that if "weathering" is occurring in this population, HBW prevalence likely will influence the observed maternal age patterns in birth weight, such that prevalence of births in normal range may resemble NH blacks, even if LBW prevalence does not. Findings suggest modest evidence of weathering in AI/AN populations for LBW. Examination of normal birth weight births suggests that inclusion of HBW to the risk profile of AI/AN births better defines birth outcome risk in this population relative to white mothers. Smoking during pregnancy and gestational diabetes were particularly prevalent among AI/AN mothers and present reason for concern in spite of relatively favorable birth outcomes.

摘要

大量研究按种族/族裔对出生结局进行了考察,不仅注意到种族/族裔差异,还发现低体重(LBW)患病率存在不同的母亲年龄模式。很少有研究考察美国印第安人/阿拉斯加原住民(AI/AN)母亲中的这些差异,尽管该人群存在严重的社会经济劣势,但其低体重患病率低于全国平均水平。先前的研究假设,由于长期承受压力、创伤和社会经济劣势,AI/AN母亲的低体重年龄模式应与非西班牙裔黑人母亲相似,但这一点尚未得到实证检验。本文使用2014 - 2016年美国出生档案中的数据,该档案包含这些年份美国所有出生记录,以考察AI/AN母亲出生体重的母亲年龄模式。重要的是,鉴于AI/AN人群中糖尿病患病率较高,本研究还考虑了高出生体重(HBW)分娩情况,并提出如果该人群中存在“健康恶化”现象,高出生体重患病率可能会影响观察到的出生体重母亲年龄模式,使得正常体重范围分娩的患病率可能与非西班牙裔黑人相似,即使低体重患病率并非如此。研究结果表明,AI/AN人群中存在低体重健康恶化的适度证据。对正常出生体重分娩的考察表明,将高出生体重纳入AI/AN分娩的风险概况,相对于白人母亲,能更好地界定该人群的出生结局风险。孕期吸烟和妊娠期糖尿病在AI/AN母亲中尤为普遍,尽管出生结局相对较好,但仍令人担忧。

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