Young D B
Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson 39216.
Am J Physiol. 1988 Nov;255(5 Pt 2):F811-22. doi: 10.1152/ajprenal.1988.255.5.F811.
Aldosterone is part of a complex system that regulates plasma potassium concentration by affecting the renal excretion of the ion as well as its distribution within the body. Because there are other components of the system, it has been difficult to determine the physiological significance of aldosterone in potassium regulation by attempting to study the hormone's effects in isolation. In this presentation a quantitative analysis of the potassium control system is used to provide information concerning the physiological role of aldosterone in potassium regulation under normal and pathological conditions, as well as during pharmacological interventions.
醛固酮是一个复杂系统的一部分，该系统通过影响离子的肾脏排泄及其在体内的分布来调节血浆钾浓度。由于该系统还有其他组成部分，试图单独研究该激素的作用来确定醛固酮在钾调节中的生理意义一直很困难。在本报告中，对钾控制系统进行了定量分析，以提供有关醛固酮在正常和病理条件下以及药物干预期间钾调节中的生理作用的信息。
