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胸外胸壁非典型深部躯体软组织平滑肌瘤:文献首例报道

Atypical deep somatic soft-tissue leiomyoma of extrathoracic chest wall: first case of the literature.

作者信息

Batihan Guntug, Usluer Ozan, Kaya Seyda Ors, Aydogdu Zekiye

机构信息

Department of Thoracic Surgery, University of Health Sciences, Dr Suat Seren Chest Diseases and Surgery, Medical Practice and Research Center, Izmir, Turkey.

Department of Clinical Pathology, University of Health Sciences, Dr Suat Seren Chest Diseases and Surgery, Medical Practice and Research Center, Izmir, Turkey.

出版信息

BMJ Case Rep. 2018 Dec 13;11(1):e226668. doi: 10.1136/bcr-2018-226668.

DOI:10.1136/bcr-2018-226668
PMID:30567239
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6301659/
Abstract

Leiomyomas are benign soft-tissue tumours which take origin from the smooth muscles. Pleura and chest wall are uncommon location for such tumours. Here, we report a case of a 26-year-old female patient presented with 3 months history of chest pain. Chest X-ray and CT showed a calcified mass of 6×12 cm in size in the left lateral of the chest wall. After resection of the mass, pathological examination diagnosed it as atypical deep somatic soft-tissue leiomyoma of extrathoracic chest wall. No pathological finding was detected during follow-up.

摘要

平滑肌瘤是起源于平滑肌的良性软组织肿瘤。胸膜和胸壁是这类肿瘤不常见的发病部位。在此,我们报告一例26岁女性患者,有3个月胸痛病史。胸部X线和CT显示胸壁左侧有一个大小为6×12厘米的钙化肿块。肿块切除后,病理检查诊断为胸壁外非典型深部躯体软组织平滑肌瘤。随访期间未发现病理异常。

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本文引用的文献

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MED12 and HMGA2 mutations: two independent genetic events in uterine leiomyoma and leiomyosarcoma.MED12和HMGA2突变:子宫平滑肌瘤和平滑肌肉瘤中的两个独立遗传事件。
Mod Pathol. 2014 Aug;27(8):1144-53. doi: 10.1038/modpathol.2013.243. Epub 2014 Jan 3.
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Cell cycle regulatory markers in uterine atypical leiomyoma and leiomyosarcoma: immunohistochemical study of 68 cases with clinical follow-up.68 例具有临床随访的子宫非典型平滑肌瘤和平滑肌肉瘤中细胞周期调控标志物的免疫组织化学研究。
Am J Surg Pathol. 2013 May;37(5):634-42. doi: 10.1097/PAS.0b013e318287779c.
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Leiomyomas requiring chest wall resection and reconstruction.需要进行胸壁切除和重建的平滑肌瘤。
Gen Thorac Cardiovasc Surg. 2014 Mar;62(3):186-90. doi: 10.1007/s11748-012-0196-y. Epub 2012 Dec 24.
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Leiomyoma of the extrapleural chest wall: an atypical location.胸腔壁外平滑肌瘤:非典型部位。
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Primary Leiomyoma of the pleura.胸膜原发性平滑肌瘤。
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Leiomyoma originating from the extrapleural tissue of the chest wall.起源于胸壁胸膜外组织的平滑肌瘤。
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Do leiomyomas of deep soft tissue exist? An analysis of highly differentiated smooth muscle tumors of deep soft tissue supporting two distinct subtypes.深部软组织平滑肌瘤是否存在?对支持两种不同亚型的深部软组织高分化平滑肌肿瘤的分析。
Am J Surg Pathol. 2001 Sep;25(9):1134-42. doi: 10.1097/00000478-200109000-00003.
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Arch Pathol Lab Med. 2000 Nov;124(11):1688-92. doi: 10.5858/2000-124-1688-SMTOTP.
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Uterine bizarre lipoleiomyoma.子宫奇异型脂肪平滑肌瘤。
Pathol Int. 1998 Jul;48(7):562-5. doi: 10.1111/j.1440-1827.1998.tb03950.x.