[Stimulating action of the albumin fraction of soluble placental proteins on T- and B-lymphocyte transformation].

Under study was the effect of the albumin fraction of soluble placental proteins on the transformation of T- and B-lymphocytes, stimulated by Salmonellae phytohemagglutinin and lipopolysaccharides, respectively. Placental proteins were separated by their fractional sedimentation with ammonium sulphate and subsequent gelfiltration on Sephadex-G-200. The albumin fraction of placental proteins was shown to stimulated the reaction of the T- and B-lymphocytes blasttransformation. Some possible mechanisms of this effect are discussed.