Children's Hospital of Soochow university.
Pediatric institute of Soochow university, Pediatric institute of Soochow university, china.
Rev Esp Enferm Dig. 2019 Jan;111(1):5-9. doi: 10.17235/reed.2018.5490/2018.
epidemiological studies that assess the association of dietary total carbohydrate intake and inflammatory bowel disease risk (IBD) have yielded controversial results. Therefore, this study of various epidemiological studies was conducted in order to explore this relationship.
a systematic literature search of the PubMed, Embase, Web of Science and Medline databases was performed up to September 2017. Cohort, case-control or cross-sectional design studies were included that reported the association of dietary carbohydrate intake and IBD risk. Summary odds ratio (OR) and the corresponding 95% CI were calculated using the random effects model.
a total of eight articles with 15 individual studies that included 1,361 cases were eligible according to the inclusion criteria. Dietary carbohydrate intake had a non-significant relationship with the risk of IBD (OR = 1.091, 95% CI = 0.817-1.455, I2 = 31.6%, pfor heterogeneity = 0.116). The pooled OR and 95% CI for ulcerative colitis (UC) and Crohn's disease (CD) with regard to dietary carbohydrate intake was 1.167 (0.777-1.752) and 1.010 (0.630-1.618), respectively. These associations were also non-significant in both European and Asia populations.
a higher dietary total carbohydrate intake had a non-significant relationship with IBD risk. Further studies with large populations are needed to verify this relationship.
评估总碳水化合物摄入量与炎症性肠病（IBD）风险之间关联的流行病学研究结果存在争议。因此，进行了这项对各种流行病学研究的荟萃分析，以探讨这种关系。
系统检索了 PubMed、Embase、Web of Science 和 Medline 数据库，截至 2017 年 9 月。纳入了报告饮食碳水化合物摄入量与 IBD 风险之间关联的队列研究、病例对照研究或横断面研究。使用随机效应模型计算汇总比值比（OR）及其相应的 95%置信区间（CI）。
根据纳入标准，共有 8 篇文章，包含 15 项符合条件的独立研究，共纳入 1361 例病例。饮食碳水化合物摄入量与 IBD 风险无显著相关性（OR = 1.091，95%CI = 0.817-1.455，I2 = 31.6%，p 异质性 = 0.116）。关于饮食碳水化合物摄入，UC 和 CD 的汇总 OR 和 95%CI 分别为 1.167（0.777-1.752）和 1.010（0.630-1.618），这些关联在欧洲和亚洲人群中均无统计学意义。
较高的饮食总碳水化合物摄入量与 IBD 风险无显著相关性。需要进一步开展大规模人群研究来验证这种关系。
