Pymer Sean A, Tew Garry A, Palmer Joanne, Ingle Lee, Smith George E, Chetter Ian C, Harwood Amy E
Academic Vascular Surgical Unit, Hull, UK.
Hull York Medical School, Hull, UK.
SAGE Open Med. 2018 Dec 10;6:2050312118818295. doi: 10.1177/2050312118818295. eCollection 2018.
The aim of this updated review is to consider the evidence base for the effectiveness of home-based exercise programmes as a treatment option for improving walking distance in patients with intermittent claudication.
The Medline, EMBASE, CINAHL, PEDro and Cochrane CENTRAL databases will be searched for terms including 'intermittent claudication', 'peripheral arterial disease', 'home-based exercise' and 'home-based walking'. No date restrictions will be used but only articles in the English language will be included. Both randomised and non-randomised trials of home-based exercise programmes versus a comparator arm will be included, and a meta-analysis using only the randomised controlled trials will be attempted if the assumptions of heterogeneity are met. Data extraction will include study details, sample description, intervention description, length of follow-up and outcomes measures. The primary outcome measure is objectively measured maximal walking distance or time, with secondary outcome measures including pain-free walking distance or time, changes in physical activity and quality of life. We will also provide a narrative description of the effective components of a home-based exercise intervention which can aid future recommendations.
Overall, this proposed review and meta-analysis aims provide a comprehensive and complete overview of the evidence base for home-based exercise programmes, which can aid clinicians in the management of their patients.
本次更新综述的目的是探讨居家锻炼计划作为改善间歇性跛行患者步行距离的一种治疗选择的证据基础。
将检索Medline、EMBASE、CINAHL、PEDro和Cochrane CENTRAL数据库，检索词包括“间歇性跛行”“外周动脉疾病”“居家锻炼”和“居家步行”。不设日期限制，但仅纳入英文文章。将纳入居家锻炼计划与对照臂比较的随机和非随机试验，如果满足异质性假设，将尝试仅使用随机对照试验进行荟萃分析。数据提取将包括研究细节、样本描述、干预描述、随访时长和结局指标。主要结局指标是客观测量的最大步行距离或时间，次要结局指标包括无痛步行距离或时间、身体活动变化和生活质量。我们还将对居家锻炼干预的有效组成部分进行叙述性描述，这有助于未来提出建议。
总体而言，本次拟进行的综述和荟萃分析旨在全面、完整地概述居家锻炼计划的证据基础，这有助于临床医生管理患者。
