Department of Plastic Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taiwan.
Department of Plastic Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taiwan.
Biomed J. 2018 Oct;41(5):321-327. doi: 10.1016/j.bj.2018.08.007. Epub 2018 Nov 6.
Patients with polytrauma are expected to have a higher risk of mortality than the summation of expected mortality for their individual injuries. This study was designed to investigate the outcome of polytrauma patients, diagnosed by abbreviated injury scale (AIS) ≥ 3 for at least two body regions, at a level I trauma center.
Detailed data of 694 polytrauma patients and 2104 non-polytrauma patients with an overall Injury Severity Score (ISS) ≥ 16 and hospitalized between January 1, 2009, and December 31, 2014 for treatment of all traumatic injuries, were retrieved from the Trauma Registry System. Two-sided Fisher exact or Pearson chi-square tests were used to compare categorical data. The unpaired Student t-test was used to analyze normally distributed continuous data, and the Mann-Whitney U-test was used to compare non-normally distributed data. Propensity-score matching in a 1:1 ratio was performed using NCSS software with logistic regression to evaluate the effect of polytrauma on in-hospital mortality.
There was no significant difference in short-term mortality between polytrauma and non-polytrauma patients, regardless of whether the comparison was made among the total patients (11.4% vs. 11.0%, respectively; p = 0.795) or among the selected propensity score-matched groups of patients following controlled covariates including sex, age, systolic blood pressure, co-morbidities, Glasgow Coma Scale scores, injury region based on AIS.
Polytrauma defined by AIS ≥3 for at least two body regions failed to recognize a significant difference in short-term mortality among trauma patients.
多发伤患者的死亡率预计高于其各部位损伤预期死亡率的总和。本研究旨在调查 I 级创伤中心至少两个身体部位损伤严重度评分(AIS)≥3 的多发伤患者的结局。
从创伤登记系统中检索了 2009 年 1 月 1 日至 2014 年 12 月 31 日期间因所有创伤性损伤住院且总体损伤严重度评分(ISS)≥16 的 694 例多发伤患者和 2104 例非多发伤患者的详细数据。使用双侧 Fisher 确切概率或 Pearson χ2 检验比较分类数据。使用独立样本 t 检验分析正态分布连续数据,使用 Mann-Whitney U 检验比较非正态分布数据。使用 NCSS 软件中的逻辑回归进行 1:1 比例的倾向评分匹配,以评估多发伤对住院死亡率的影响。
无论在所有患者中(分别为 11.4%和 11.0%;p=0.795)还是在控制协变量(包括性别、年龄、收缩压、合并症、Glasgow 昏迷评分、基于 AIS 的损伤部位)后进行倾向评分匹配的患者中,多发伤与非多发伤患者的短期死亡率均无显著差异。
AIS≥3 定义的多发伤未能识别出至少两个身体部位损伤的创伤患者短期死亡率的显著差异。