Buzunov V O, Prykaschykova K Y, Yaroshenko Zh S, Kostiuk G V, Gubina I G
State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», 53, Melnykova str., Kyiv, 04050, Ukraine.
Probl Radiac Med Radiobiol. 2018 Dec;23:107-119. doi: 10.33145/2304-8336-2018-23-107-119.
to study post-accident levels of illnesses system diseases of residents from radioactively contaminatedareas aged 0-60 years on the date of the Chornobyl accident, and to analyze the effect of chronic low-dose ionizingradiation.
Epidemiological research and analysis of morbidity of circulatory system diseases of resi-dents of radioactively contaminated areas (RCA) has been carried out. The individuals who were studied includedRCA residents aged 0-60 (98, 902 persons) on the date of the Chornobyl accident. The data of the victims' annualmedical examinations during 1988-2016 were received from the State Register of Ukraine (SRU). Detection of thepossible dependence of the development of circulatory system diseases on the effects of ionizing radiation was car-ried out in the range of individual total effective doses ranging from 13-40 mSv and more as accumulated over26 years after the Chornobyl accident. The control group consisted of individuals with a radiation dose of <13 mSv.The statistical analysis of data was performed using the Microsoft Office Excel 2013 software packages.
For the entire period of the study, 20,552 cases of circulatory system diseases were detected for the firsttime (ID at 103 person-years is 15.66 ± 0.11), incl. men, respectively, 7,211 cases (12.32 ± 0.14), women - 13,341cases (18.35 ± 0.16). It has been determined that among the circulatory system diseases of RZT residents there isthe most express display of ischemic heart disease, a disease characterized by high blood pressure, including otherheart diseases. The dependence of the levels of morbidity on the diseases of the circulatory system on the sex ofvictims was established. A connection has been established between the development of certain circulatory systemdiseases and the amounts of individual total effective doses of ionizing radiation accumulated over the period of1986-2012. Individual total effective doses of ionizing radiation in men and women in the range of doses of13-40 mSv or more.
On the basis of cohort epidemiological studies, there was studied the dynamics of levels of circulatory system diseases among the RCT residents aged 0-60 years on the date of the Chornobyl accident during the observation period of 1988-2016. The overstated levels of cardiovascular and cerebrovascular diseases were established in the first twelve post-accident years, especially in the first six years. The highest morbidity rates for circulatory system diseases were identified in women over men. The development of certain circulatory system diseases, both in men and women, in a certain period is associated with the amount of dose of ionizing radiation from radionuclides 134Сs, 137Сs.
研究切尔诺贝利事故发生当日年龄在0至60岁的受放射性污染地区居民事故后的疾病（系统疾病）水平，并分析慢性低剂量电离辐射的影响。
对受放射性污染地区（RCA）居民循环系统疾病的发病率进行了流行病学研究与分析。研究对象包括切尔诺贝利事故发生当日年龄在0至60岁的RCA居民（98902人）。1988 - 2016年受害者年度体检数据来自乌克兰国家登记册（SRU）。在切尔诺贝利事故后26年累计的个体总有效剂量范围为13 - 40 mSv及以上的情况下，检测循环系统疾病发展与电离辐射影响之间的可能相关性。对照组由辐射剂量<13 mSv的个体组成。使用Microsoft Office Excel 2013软件包对数据进行统计分析。
在整个研究期间，首次检测到20552例循环系统疾病病例（每103人年发病率为15.66±0.11），其中男性分别为7211例（12.32±0.14），女性为13341例（18.35±0.16）。已确定在RZT居民的循环系统疾病中，缺血性心脏病表现最为明显，该疾病以高血压为特征，还包括其他心脏病。确定了循环系统疾病发病率水平与受害者性别之间的相关性。已确定某些循环系统疾病的发展与1986 - 2012年期间积累的个体总有效电离辐射剂量之间存在关联。男性和女性的个体总有效电离辐射剂量在13 - 40 mSv或更高剂量范围内。
基于队列流行病学研究，研究了1988 - 2016年观察期内切尔诺贝利事故发生当日年龄在0至60岁的RCT居民循环系统疾病水平的动态变化。事故后的头十二年，尤其是头六年，心血管和脑血管疾病水平被高估。循环系统疾病的发病率女性高于男性。在一定时期内，男性和女性某些循环系统疾病的发展与放射性核素134Сs、137Сs的电离辐射剂量有关。
