Zavadenko A N, Medvedev M I, Degtyareva M G
Pirogov Russian National Research Medical University, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(11):35-42. doi: 10.17116/jnevro201811811135.
To assess psychomotor development in infants with neonatal seizures (NS) born with different gestational age, by means of Bayley-III scales of infant and toddler development, in their corrected age of 1 year.
The study included 52 infants, who had NS and were born with different gestational age: 28 weeks or less (n=26) - group I, 29-32 weeks (n=16) - group II, 33-36 weeks (n=3) - group III, 37-41 weeks (n=7) - group IV. The infants' neurodevelopment was evaluated in their corrected age of 1 year by means of N. Bayley scales of infant and toddler development, third edition: Cognitive, Language, Motor, Social-Emotional, and Adaptive Behavior.
Only 17 (32,7%) of 52 examined infants did not demonstrate any developmental delay on each of five Bayley-III scales. Significant developmental delay (composite score <70) on at least one scale was revealed in 23 (44,2%) patients, including 12 (46,2%) in group I, 5 (31,3%) in group II, 6 (60%) of 10 in the combined group III-IV. In most cases, neurodevelopmental delays were attributed to only one domain and could be indicated as partial. The conclusion about global developmental retardation (the composite scores 55 or less on all five scales) was done in 3 patients, each of whom had a co-morbidity of cerebral palsy and epilepsy.
采用贝利婴幼儿发展量表第三版，评估不同胎龄出生的新生儿惊厥（NS）婴儿在1岁矫正年龄时的心理运动发育情况。
本研究纳入52例患有NS且胎龄不同的婴儿：28周及以下（n = 26）——第一组，29 - 32周（n = 16）——第二组，33 - 36周（n = 3）——第三组，37 - 41周（n = 7）——第四组。采用贝利婴幼儿发展量表第三版，在1岁矫正年龄时对婴儿的神经发育进行评估：认知、语言、运动、社会情感和适应性行为。
52例接受检查的婴儿中，只有17例（32.7%）在贝利-III量表的五个维度上均未表现出发育迟缓。23例（44.2%）患者至少在一个维度上出现显著发育迟缓（综合得分<70），其中第一组12例（46.2%），第二组5例（31.3%），第三组和第四组合并组10例中的6例（60%）。在大多数情况下，神经发育迟缓仅归因于一个领域，可称为部分性。3例患者被判定为整体发育迟缓（所有五个维度的综合得分均为55或更低），每例均合并脑瘫和癫痫。
