Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie gory 1-3, Moscow 119991, Russia.
N. M. Emanuel Institute of Biochemical Physics, Russia Academy of Sciences, Kosygina 4, Moscow 119334, Russia.
Molecules. 2018 Dec 24;24(1):57. doi: 10.3390/molecules24010057.
A simple method has been developed for the synthesis of cyclopropa[]coumarins, which belong to the donor-acceptor cyclopropane family and, therefore, are promising substrates for the preparation of chromene-based fine chemicals. The method, based on the acetic acid-induced intramolecular transesterification of 2-arylcyclopropane-1,1-dicarboxylates, was found to be efficient for substrates containing hydroxy group directly attached to the aromatic ring.
已经开发出一种简单的方法来合成环丙[]香豆素，它属于给体-受体环丙烷家族，因此是制备色烯基精细化学品的有前途的底物。该方法基于 2-芳基环丙烷-1,1-二羧酸酯在乙酸诱导下的分子内酯交换，对于直接连接在芳环上的含有羟基的底物是有效的。
