Yuan Zhen, Yu Mei, Chen Yu
Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China,
Department of Obstetrics and Gynecology, LuHe hospital, Capital Medical University, Beijing, China.
Onco Targets Ther. 2018 Dec 20;12:113-117. doi: 10.2147/OTT.S180309. eCollection 2019.
Ovarian anaplastic ependymoma is a rare gynecologic malignancy. Owing to its rarity, treatment is challenging. Unilateral ovarian ependymoma was found during laparoscopy in a 19-year-old woman. After cytoreductive surgery, three cycles of bleomycin, etoposide, and cisplatin were administered. Four years after chemotherapy, the patient experienced relapse. After the secondary cytoreductive surgery, no further treatment was performed. She is in good condition, ~19 months after secondary cytoreductive surgery using hormone-replacement therapy without chemotherapy. Some cases of ovarian ependymoma can be treated with surgery alone without chemotherapy and the outcome has been satisfying. Choosing treatment based on malignant ovarian germ cell tumors may be not optimal. Therefore, we suggest individualized treatment for ovarian ependymoma.
卵巢间变性室管膜瘤是一种罕见的妇科恶性肿瘤。由于其罕见性，治疗具有挑战性。一名19岁女性在腹腔镜检查时发现单侧卵巢室管膜瘤。在进行肿瘤细胞减灭术后，给予了三个周期的博来霉素、依托泊苷和顺铂化疗。化疗四年后，患者复发。二次肿瘤细胞减灭术后，未进行进一步治疗。在使用激素替代疗法而非化疗进行二次肿瘤细胞减灭术后约19个月，她状况良好。部分卵巢室管膜瘤病例仅通过手术治疗而无需化疗，且效果令人满意。基于恶性卵巢生殖细胞肿瘤选择治疗方案可能并非最佳。因此，我们建议对卵巢室管膜瘤进行个体化治疗。
