设计和演示一种可配置的成像平台，用于结合激光、超声和弹性成像。
Design and Demonstration of a Configurable Imaging Platform for Combined Laser, Ultrasound, and Elasticity Imaging.
出版信息
IEEE Trans Med Imaging. 2019 Jul;38(7):1622-1632. doi: 10.1109/TMI.2018.2889736. Epub 2018 Dec 27.
Abstract
This paper introduces a configurable combined laser, ultrasound, and elasticity (CLUE) imaging platform. The CLUE platform enables imaging sequences capable of simultaneously providing quantitative acoustic, optical, and mechanical contrast for comprehensive diagnosis and monitoring of complex diseases, such as cancer. The CLUE imaging platform was developed on a Verasonics ultrasound scanner integrated with a pulsed laser, and it was designed to be modular and scalable to allow researchers to create their own specific imaging sequences efficiently. The CLUE imaging platform and sequence were demonstrated in a tissue-mimicking phantom containing a stiff inclusion labeled with optically-activated nanodroplets and in an ex vivo mouse spleen. We have shown that CLUE imaging can simultaneously capture multi-functional imaging signals providing quantitative information on tissue.
摘要
本文介绍了一种可配置的组合式激光、超声和弹性（CLUE）成像平台。该 CLUE 平台支持成像序列，能够同时提供定量声学、光学和机械对比，用于复杂疾病（如癌症）的综合诊断和监测。CLUE 成像平台是在集成了脉冲激光器的 Verasonics 超声扫描仪上开发的，其设计具有模块化和可扩展性，可使研究人员高效地创建自己的特定成像序列。CLUE 成像平台和序列已在含有用光学激活纳米液滴标记的刚性内含物的组织模拟体和离体小鼠脾脏中进行了演示。我们已经表明，CLUE 成像可以同时捕获多功能成像信号，提供关于组织的定量信息。
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2
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3
Combined Multiwavelength Photoacoustic and Plane-Wave Ultrasound Imaging for Probing Dynamic Phase-Change Contrast Agents.联合多波长光声和平面波超声成像用于探测动态相变化造影剂。
IEEE Trans Biomed Eng. 2019 Feb;66(2):595-598. doi: 10.1109/TBME.2018.2849077. Epub 2018 Jun 20.
4
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5
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Ultrasound Med Biol. 2018 Jan;44(1):37-70. doi: 10.1016/j.ultrasmedbio.2017.09.012. Epub 2017 Oct 26.
6
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