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防腐液的抗菌能力:一项对比研究。

The antimicrobial capacity of embalming solutions: a comparative study.

机构信息

Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.

出版信息

J Appl Microbiol. 2019 Mar;126(3):764-770. doi: 10.1111/jam.14191. Epub 2019 Jan 16.

Abstract

AIMS

Infectious health risks are associated with handling human cadavers and to decrease such risks, cadavers are embalmed using different chemicals. The aim of this study is to quantify the amount of micro-organisms present in different regions of human cadavers before embalming, after embalming and over a period of 8 months.

METHODS AND RESULTS

Human cadavers were embalmed using Thiel, formalin, Genelyn and the Imperial College London soft-preservation (ICL-SP) solution with two cadavers per technique. Sterile swabs were used to collect samples from different regions. Samples were collected every 2 months. All cadavers had a high number of microbial colonies before embalming. While no colonies were detected on formalin and Genelyn embalmed cadavers post-embalming, the number of colonies decreased significantly in Thiel-embalmed cadavers and stayed relatively the same in ICL-SP-embalmed cadavers.

CONCLUSIONS

Formalin-embalmed cadavers showed the strongest disinfecting abilities followed by Thiel-embalmed cadavers, then Genelyn-embalmed cadavers and finally by ICL-SP cadavers.

SIGNIFICANCE AND IMPACT OF THE STUDY

This study highlights how under researched this area is and the evident variation in the antimicrobial abilities of different embalming solutions on the cadaver as a whole and within different regions of the same cadaver.

摘要

目的

处理人体尸体与传染性健康风险有关,为降低此类风险,人们使用不同的化学物质对尸体进行防腐处理。本研究旨在量化人体尸体在防腐处理前、处理后以及 8 个月内不同部位存在的微生物数量。

方法和结果

使用 Thiel、福尔马林、Genelyn 和伦敦帝国学院软保存(ICL-SP)溶液对 2 具尸体进行防腐处理。使用无菌拭子从不同部位采集样本。每两个月采集一次样本。所有尸体在防腐处理前都有大量的微生物菌落。福尔马林和 Genelyn 防腐处理后的尸体中未检测到菌落,但 Thiel 防腐处理后的尸体中的菌落数量显著减少,而 ICL-SP 防腐处理后的尸体中的菌落数量相对保持不变。

结论

福尔马林防腐处理的尸体显示出最强的消毒能力,其次是 Thiel 防腐处理的尸体,然后是 Genelyn 防腐处理的尸体,最后是 ICL-SP 防腐处理的尸体。

研究意义和影响

本研究强调了该领域研究的不足,以及不同防腐溶液对整个尸体以及同一尸体不同部位的抗菌能力存在明显差异。

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