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未诊断的高血糖和高血压作为塞尔维亚学生群体未来心血管疾病各种危险因素的指标。

Undiagnosed Hyperglycaemia and Hypertension as Indicators of the Various Risk Factors of Future Cardiovascular Disease Among Population of Serbian Students.

作者信息

Georgiev Andrijana Milošević, Krajnović Dušanka, Kotur-Stevuljević Jelena, Ignjatović Svetlana, Marinković Valentina

机构信息

University of Belgrade, Faculty of Pharmacy, Belgrade, Serbia.

Center for the Study of Bioethics, Belgrade, Serbia.

出版信息

J Med Biochem. 2018 Jul 1;37(3):289-298. doi: 10.1515/jomb-2017-0059. eCollection 2018 Jul.

Abstract

BACKGROUND

A number of risk behaviours, such as smoking, overweight, excessive alcohol intake, insufficient physical activity, excessive and frequent intake of salt, reduced fruit and vegetable intake, increased fat intake, which constitute living habits of an individual can influence the occurrence of hypertension and hyperglycaemia. The changing of these lifestyles can reduce the risk of developing prehypertension and prediabetes.

METHODS

The survey was conducted at student's campuses. The respondents were subjected to the height, weight, blood glucose and blood pressure. Respondents filled in previously created questionnaire that was approved by the Ethics Committee for Biomedical Research Faculty of Pharmacy, University of Belgrade.

RESULTS

The percentage of respondents with a glucose value above the reference value was 14.6% (n=19), 2.4% (n=3) had values greater than 7 mmol/L without being diagnosed with diabetes, and accordingly, 2.4% (n=3) had elevated HbA1c values (above 42 mmol/mol or 6.0%). The percentage of respondents with elevated systolic and diastolic blood pressure was 14.9% and 7.4% respectively. Regarding calculated risk scores, they showed parallel increase with increas-ing of BMI (HPS), systolic and diastolic pressure (OHS), and glucose concentration (OPS).

CONCLUSIONS

When analysing all the factors that could cause the later development of diabetes, which is associated with hypertension as well, it is observed that the student population is very much exposed to those factors. The results of this study cannot be representative for the general population of students, but they can provide recommendations for further research.

摘要

背景

一些风险行为,如吸烟、超重、过量饮酒、体育活动不足、过度频繁摄入盐分、蔬果摄入量减少、脂肪摄入量增加,这些构成个人生活习惯的因素会影响高血压和高血糖的发生。改变这些生活方式可降低患高血压前期和糖尿病前期的风险。

方法

调查在学生校园内进行。对受访者测量身高、体重、血糖和血压。受访者填写先前制定并经贝尔格莱德大学药学院生物医学研究伦理委员会批准的问卷。

结果

血糖值高于参考值的受访者比例为14.6%(n = 19),2.4%(n = 3)的值大于7 mmol/L但未被诊断为糖尿病,相应地,2.4%(n = 3)的糖化血红蛋白值升高(高于42 mmol/mol或6.0%)。收缩压和舒张压升高的受访者比例分别为14.9%和7.4%。关于计算出的风险评分,它们随体重指数(HPS)、收缩压和舒张压(OHS)以及血糖浓度(OPS)的升高而呈平行增加。

结论

在分析所有可能导致日后患糖尿病(其也与高血压相关)的因素时,发现学生群体极易受到这些因素影响。本研究结果不能代表全体学生,但可为进一步研究提供建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cad/6298463/bea976f2b320/jomb-37-289-g001.jpg

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