Stern L
Regency Park Centre for Young Disabled, Adelaide, South Australia.
Aust Paediatr J. 1988;24 Suppl 1:34-6.
A number of imaging techniques has been used in Duchenne muscular dystrophy and other neuromuscular conditions. Ultrasound reflects the changes occurring in muscle and allows differentiation between myopathies and neuropathies. It may also be of help in deciding where to take a needle biopsy. Computerized tomography (CT) has been used to assess progression over a 6 month period in Duchenne dystrophy. The density changes observed on CT scans give an accurate indication of progression and will be a useful tool in clinical trials. CT scans of obligate carriers of Duchenne dystrophy showed lower muscle densities than male controls. Magnetic resonance imaging also accurately reflects pathological changes in muscle. A pilot project to improve respiratory muscle strength and endurance showed that it was possible to improve endurance. A longer term project is currently being carried out to improve respiratory muscle endurance by the use of computer games connected to a thermistor. A certain inspiratory effort is required to continue the games, which provide the motivating factor.
许多成像技术已用于杜氏肌营养不良症和其他神经肌肉疾病。超声可反映肌肉中发生的变化，并有助于区分肌病和神经病。它在决定何处进行针吸活检时也可能有所帮助。计算机断层扫描（CT）已用于评估杜氏肌营养不良症6个月期间的病情进展。CT扫描上观察到的密度变化能准确显示病情进展，将成为临床试验中的有用工具。杜氏肌营养不良症携带者的CT扫描显示，其肌肉密度低于男性对照组。磁共振成像也能准确反映肌肉的病理变化。一个旨在提高呼吸肌力量和耐力的试点项目表明，提高耐力是可能的。目前正在开展一个长期项目，通过使用连接热敏电阻的电脑游戏来提高呼吸肌耐力。继续玩游戏需要一定的吸气努力，这提供了激励因素。
