Hasegawa T, Matsumura K, Hashimoto T, Ikehira H, Fukuda H, Tateno Y
Department of Neurology, Shimoshizu National Hospital.
Rinsho Shinkeigaku. 1992 Mar;32(3):333-5.
Intramuscular degeneration process of Duchenne dystrophy skeletal muscles was investigated by longitudinal skeletal muscle imaging with high-field-strength NMR-CT of 1.5 Tesla. Thigh muscles in 10 cases ranging in age from 4 to 19 years were examined by T1-weighed longitudinal images (TR = 215-505 ms, TE = 19-20 ms). Following results were obtained: (1) Skeletal muscle degeneration was depicted as high signal intensity area reflecting its high fat contents. (2) These high signal intensity areas had a longitudinally streaky appearance in parallel direction with myofibers. (3) These findings were more prominent toward myotendon junction than muscle bellies. (4) Skeletal muscle degeneration progressed rapidly between 7 to 10 years of age, and reached a plateau after that.
采用1.5特斯拉高场强核磁共振-CT对杜氏肌营养不良症骨骼肌的肌内变性过程进行了纵向骨骼肌成像研究。对10例年龄在4至19岁之间的大腿肌肉进行了T1加权纵向图像检查（TR = 215 - 505毫秒，TE = 19 - 20毫秒）。获得了以下结果：（1）骨骼肌变性表现为反映其高脂肪含量的高信号强度区域。（2）这些高信号强度区域在与肌纤维平行的方向上呈纵向条纹状外观。（3）这些发现朝向肌腱连接处比肌腹处更明显。（4）骨骼肌变性在7至10岁之间进展迅速，之后达到平台期。
