Sun Jia, Yu Jin-Hai, Zhang Jun-Sheng, Song Xiu-Qing, Bao Jie, Zhang Hua
School of Chemistry and Chemical Engineering, University of Jinan, 336 West Road of Nan Xinzhuang, Jinan, 250022, P. R. China.
School of Biological Science and Technology, University of Jinan, 336 West Road of Nan Xinzhuang, Jinan, 250022, P. R. China.
Chem Biodivers. 2019 Mar;16(3):e1800581. doi: 10.1002/cbdv.201800581. Epub 2019 Feb 25.
Fourteen chromane derivatives of seven pairs of enantiomers (1-14) have been obtained from the ethanolic extract of the flower buds of Tussilago farfara L. Their structures with absolute configurations have been elucidated by detailed spectroscopic analyses, chemical methods, and particularly comparison of experimental ECD spectra with theoretically computed ones. Biological evaluations revealed that they did not show cytoprotective, antimicrobial, and α-glucosidase inhibitory activities.
从款冬花的乙醇提取物中获得了七对对映体的14种色满衍生物（1-14）。通过详细的光谱分析、化学方法，特别是将实验ECD光谱与理论计算光谱进行比较，阐明了它们的结构及其绝对构型。生物学评价表明，它们没有表现出细胞保护、抗菌和α-葡萄糖苷酶抑制活性。
