BACKGROUND

Accurate and repeatable measurements of the retinal nerve fibre layer (RNFL) thickness are important in the diagnosis and management of glaucoma and other disorders.

OBJECTIVE

To assess the repeatability and reproducibility of the iVue-100 optical coherence tomographer (OCT).

METHODS

The thickness of the RNFL was measured for 50 healthy participants using the iVue-100 OCT. Although both eyes per participant were measured, only right eyes were analysed here. Repeatability and reproducibility of the iVue-100 OCT were assessed using the intraclass correlation coefficient (ICC), coefficient of variation (CoV), paired t-tests and Bland-Altman analysis.

RESULTS

Good intra-observer repeatability was obtained as indicated by the ICC of observer 1 (range: 0.941 - 0.976) and observer 2 (range: 0.829 - 0.953) as well by the CoV of observer 1 (range: 0.098 - 0.137) and observer 2 (0.091 - 0.132). In terms of inter-observer reproducibility, significant differences (p< 0.05) in mean measurements between the observers were noted for the average RNFL readings and in the superior and inferior quadrants as assessed with paired t-tests. Even though significant inter-session differences were found for the average RNFL thickness and the superior quadrant (p = 0.003 and p = 0.013, respectively), excellent ICCs were obtained for inter-session reproducibility (range: 0.914 - 0.979).

CONCLUSION

The iVue-100 OCT demonstrated good repeatability and reproducibility for RNFL thickness measurements.