三维组织/器官打印的当前进展。
Current advances in three-dimensional tissue/organ printing.
作者信息
Park Jeong Hun, Jang Jinah, Lee Jung-Seob, Cho Dong-Woo
机构信息
1Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
2Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-ro, Nam-gu, Pohang, 37673 Korea.
出版信息
Tissue Eng Regen Med. 2016 Dec 17;13(6):612-621. doi: 10.1007/s13770-016-8111-8. eCollection 2016 Dec.
Three-dimensional (3D) tissue/organ printing is a major aspect of recent innovation in the field of tissue engineering and regenerative medicine. 3D tissue/organ printing aims to create 3D living tissue/organ analogues, and have evolved along with advances in 3D printing techniques. A diverse range of computer-aided 3D printing techniques have been applied to dispose living cells together with biomaterials and supporting biochemical factors within pre-designed 3D tissue/organ analogues. Recent developments in printable biomaterials, such as decellularized extracellular matrix bio-inks have enabled improvements in the functionality of the resulting 3D tissue/organ analogues. Here, we provide an overview of the 3D printing techniques and biomaterials that have been used, including the development of 3D tissue/organ analogues. In addition, models are described, and future perspectives in 3D tissue/organ printing are identified.
三维（3D）组织/器官打印是组织工程和再生医学领域近期创新的一个主要方面。3D组织/器官打印旨在创建3D活组织/器官类似物，并随着3D打印技术的进步而发展。各种各样的计算机辅助3D打印技术已被应用于将活细胞与生物材料以及支持性生化因子一起放置在预先设计的3D组织/器官类似物中。可打印生物材料的最新进展，如脱细胞细胞外基质生物墨水，已使所得3D组织/器官类似物的功能得到改善。在这里，我们概述了已使用的3D打印技术和生物材料，包括3D组织/器官类似物的发展。此外，还描述了模型，并确定了3D组织/器官打印的未来前景。
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