Zhao Yang, Guo Wei
Department of Respiratory Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei, PR China.
Department of Pathology, Basic Medical Sciences of Wuhan University, Wuhan, Hubei, PR China.
Respir Med Case Rep. 2018 Dec 15;26:150-153. doi: 10.1016/j.rmcr.2018.12.008. eCollection 2019.
Primary pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma is extremely rare. MALT lymphoma patients usually show no clinical symptoms or physical signs. Chest radiograph or computed tomography (CT) may confuse MALT lymphoma with other pulmonary diseases, which would lead to misdiagnosis or a delayed diagnosis. In the present study, a 33-year-old male patient had cough and fever. Chest CT showed consolidation on both sides. Those clinical symptoms disappeared after he had been misdiagnosed and treated for community-acquired pneumonia for three weeks. However, further chest CT still showed the consolidation without any change. Then an ultrasonic guided transthoracic needle biopsy was performed. Morphological changes indicated the diagnosis of extranodal marginal Zone B cell lymphoma of MALT. The patient was then treated with chemotherapy and rituximab. After this line of treatment, the consolidation decreased.
原发性肺黏膜相关淋巴组织（MALT）淋巴瘤极为罕见。MALT淋巴瘤患者通常无临床症状或体征。胸部X线片或计算机断层扫描（CT）可能会将MALT淋巴瘤与其他肺部疾病混淆，从而导致误诊或诊断延迟。在本研究中，一名33岁男性患者有咳嗽和发热症状。胸部CT显示双侧实变。在被误诊为社区获得性肺炎并接受三周治疗后，这些临床症状消失。然而，进一步的胸部CT仍显示实变无任何变化。随后进行了超声引导下经胸针吸活检。形态学改变提示诊断为MALT结外边缘区B细胞淋巴瘤。该患者随后接受了化疗和利妥昔单抗治疗。经过这一系列治疗后，实变减轻。
