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扫频源光学相干断层扫描技术在健康人群中获取的视网膜和视盘测量结果的可重复性和可靠性

Reproducibility and reliability of retinal and optic disc measurements obtained with swept-source optical coherence tomography in a healthy population.

作者信息

Satue Maria, Gavin Alicia, Orduna Elvira, Vilades Elisa, Rodrigo Maria Jesus, Obis Javier, Polo Vicente, Larrosa Jose Manuel, Pablo Luis Emilio, Garcia-Martin Elena

机构信息

Ophthalmology Department, Miguel Servet University Hospital, C/ Padre Arrupe, Consultas Externas de Oftalmología, 50009, Zaragoza, Spain.

Aragon Institute for Health Research (IIS Aragón), Miguel Servet Ophthalmology Innovative and Research Group (GIMSO), Zaragoza, Spain.

出版信息

Jpn J Ophthalmol. 2019 Mar;63(2):165-171. doi: 10.1007/s10384-018-00647-2. Epub 2019 Jan 2.

DOI:10.1007/s10384-018-00647-2
PMID:30604113
Abstract

PURPOSE

To analyze the reproducibility of macular and peripapillary thickness measurements, and optic nerve morphometric data obtained with Triton Optical coherence tomography (OCT) in a healthy population.

STUDY DESIGN

Observational cross sectional study.

MATERIAL AND METHODS

A total of 108 eyes underwent evaluation using the Triton Swept Source-OCT. A wide protocol was used and measurements in each eye were repeated three times. Morphometric data of the optic nerve head, full macular thickness, ganglion cell layer (GCL) and retinal nerve fiber layer thickness (RNFL) were analyzed. For each parameter, the coefficient of variation (COV) and the intra-class (ICC) correlation values were calculated.

RESULTS

Measurements were highly reproducible for all morphometric measurements of the optic disc, with a mean COV of 6.36%. Macular full thickness showed good COV and ICC coefficients, with a mean COV value of 1.00%. Macular GCL thickness showed a mean COV value of 3.06%, and ICC higher than 0.787. Peripapillary RNFL thickness showed good COV and ICC coefficients, with a mean COV value of 8.31% and ICC higher than 0.684. The inferotemporal sector showed the lowest ICC (0.685).

CONCLUSIONS

Triton OCT presents good reproducibility values in measurements corresponding to retinal parameters, with macular measurements showing the highest reproducibility rates. Peripapillary RNFL measurements should be evaluated with caution.

摘要

目的

分析在健康人群中使用Triton光学相干断层扫描(OCT)获得的黄斑和视乳头周围厚度测量值以及视神经形态学数据的可重复性。

研究设计

观察性横断面研究。

材料与方法

总共108只眼睛接受了Triton扫频源OCT评估。采用广泛的方案,每只眼睛的测量重复三次。分析视神经乳头的形态学数据、黄斑全层厚度、神经节细胞层(GCL)和视网膜神经纤维层厚度(RNFL)。对于每个参数,计算变异系数(COV)和组内相关系数(ICC)值。

结果

对视盘的所有形态学测量,测量结果具有高度可重复性,平均COV为6.36%。黄斑全层厚度显示出良好的COV和ICC系数,平均COV值为1.00%。黄斑GCL厚度的平均COV值为3.06%,ICC高于0.787。视乳头周围RNFL厚度显示出良好的COV和ICC系数,平均COV值为8.31%,ICC高于0.684。颞下象限显示出最低的ICC(0.685)。

结论

Triton OCT在视网膜参数测量中呈现出良好的可重复性值,其中黄斑测量的可重复性率最高。对视乳头周围RNFL测量应谨慎评估。

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