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腹腔镜 IPOM 与开放式下修补术治疗择期切口疝修补术的比较:基于注册的、倾向评分匹配的 9907 例患者比较。

Laparoscopic IPOM versus open sublay technique for elective incisional hernia repair: a registry-based, propensity score-matched comparison of 9907 patients.

机构信息

Department of Surgery, Center for Minimally Invasive Surgery, Academic Teaching Hospital of Charité Medical School, Vivantes Hospital, Neue Bergstrasse 6, 13585, Berlin, Germany.

Department of General and Visceral Surgery, GRN - Hospital Weinheim, Röngtenstraße 1, 69469, Weinheim, Germany.

出版信息

Surg Endosc. 2019 Oct;33(10):3361-3369. doi: 10.1007/s00464-018-06629-2. Epub 2019 Jan 2.

Abstract

BACKGROUND

For comparison of laparoscopic IPOM versus sublay technique for elective incisional hernia repair, the number of cases included in randomized controlled trials and meta-analyses is limited. Therefore, an urgent need for more comparative data persists.

METHODS

In total, 9907 patients with an elective incisional hernia repair and 1-year follow-up were selected from the Herniamed Hernia Registry between September 1, 2009 and June 1, 2016. Using propensity score matching, 3965 (96.5%) matched pairs from 4110 laparoscopic IPOM and 5797 sublay operations were formed for comparison of the techniques.

RESULTS

Comparison of laparoscopic IPOM versus open sublay revealed disadvantages for the sublay operation regarding postoperative surgical complications (3.4% vs. 10.5%; p < 0.001), complication-related reoperations (1.5% vs. 4.7%; p < 0.001), and postoperative general complications (2.5% vs. 3.7%; p = 0.004). The majority of surgical postoperative complications were surgical site infection, seroma, and bleeding. Laparoscopic IPOM had disadvantages in terms of intraoperative complications (2.3% vs. 1.3%; p < 0.001), mainly bleeding, bowel, and other organ injuries. No significant differences in the recurrence and pain rates at 1-year follow-up were observed.

CONCLUSION

Laparoscopic IPOM was found to have advantages over the open sublay technique regarding the rates of both surgical and general postoperative complications as well as complication-related reoperations, but disadvantages regarding the rate of intraoperative complications.

摘要

背景

为了比较腹腔镜 IPOM 与下修补术治疗择期切口疝的效果,随机对照试验和荟萃分析纳入的病例数量有限。因此,迫切需要更多的对比数据。

方法

本研究从 2009 年 9 月 1 日至 2016 年 6 月 1 日期间的 Herniamed 疝登记处中选择了 9907 例择期切口疝修补术和 1 年随访的患者。使用倾向评分匹配,从 4110 例腹腔镜 IPOM 和 5797 例下修补术的手术中,形成了 3965 对(96.5%)匹配的手术进行比较。

结果

腹腔镜 IPOM 与开放下修补术的比较显示,下修补术在术后手术并发症(3.4%比 10.5%;p<0.001)、与并发症相关的再次手术(1.5%比 4.7%;p<0.001)和术后一般并发症(2.5%比 3.7%;p=0.004)方面存在劣势。大多数手术术后并发症为手术部位感染、血清肿和出血。腹腔镜 IPOM 在术中并发症(2.3%比 1.3%;p<0.001)方面存在劣势,主要是出血、肠道和其他器官损伤。在 1 年随访时,复发率和疼痛率无显著差异。

结论

腹腔镜 IPOM 在下修补术方面具有优势,在手术和术后一般并发症以及与并发症相关的再次手术方面具有优势,但在术中并发症方面存在劣势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed25/6722046/484c22289ece/464_2018_6629_Fig1_HTML.jpg

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