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实体器官移植后的皮肤癌筛查:加拿大实践调查。

Skin cancer screening after solid organ transplantation: Survey of practices in Canada.

机构信息

Women's College Research Institute, Women's College Hospital, Toronto, Canada.

Department of Medicine, University of Toronto, Toronto, Canada.

出版信息

Am J Transplant. 2019 Jun;19(6):1792-1797. doi: 10.1111/ajt.15224. Epub 2019 Jan 23.

Abstract

Guidelines recommend annual dermatology screening after solid organ transplantation to facilitate early detection of keratinocyte carcinoma (nonmelanoma skin cancer), the most common posttransplant malignancy. There are limited data on adherence levels and barriers to screening. We conducted a cross-sectional survey of 477 physicians and nurses providing posttransplant care in Canada. The questionnaire asked about skin cancer screening and education practices, including the perceived importance and barriers. Whereas care providers viewed skin cancer screening as important for adult patients (median rating of 10/10, interquartile range 8-10), only 53% ensured annual screening for white adult transplant recipients. Having a screening policy in place (adjusted odds ratio 6.78, 95% confidence interval 3.12-14.74) and a dermatologist present at the transplant center (adjusted odds ratio 2.19, 95% confidence interval 1.03-4.67) were independently associated with higher adherence. Long wait times, lack of specialized transplant dermatologists, long travel distances, and insufficient priority were cited as the most common barriers for access to dermatologic care. Skin cancer education was provided to patients by over three quarters of care providers. Given the self-reported lack of adherence to annual skin cancer screening, there is need to develop, evaluate, and implement interventions that improve screening rates and skin cancer outcomes.

摘要

指南建议在实体器官移植后每年进行皮肤科筛查,以促进角质细胞癌(非黑色素瘤皮肤癌)的早期发现,这是移植后最常见的恶性肿瘤。关于筛查的依从水平和障碍的数据有限。我们对在加拿大提供移植后护理的 477 名医生和护士进行了横断面调查。调查问卷询问了皮肤癌筛查和教育实践,包括对重要性和障碍的看法。虽然护理提供者认为皮肤癌筛查对成年患者很重要(中位数评分为 10/10,四分位间距为 8-10),但只有 53%的白人成年移植受者确保了每年进行筛查。制定筛查政策(调整后的优势比为 6.78,95%置信区间为 3.12-14.74)和移植中心有皮肤科医生(调整后的优势比为 2.19,95%置信区间为 1.03-4.67)与更高的依从性独立相关。就诊时间长、缺乏专门的移植皮肤科医生、旅行距离长和优先级不足被认为是获得皮肤科护理的最常见障碍。超过四分之三的护理提供者向患者提供了皮肤癌教育。鉴于自我报告的对年度皮肤癌筛查的依从性不足,需要制定、评估和实施干预措施,以提高筛查率和皮肤癌结果。

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