Sağlık Bilimleri University Dr Suat Seren Chest Disease & Surgery Training & Research Hospital, Department of Pulmonology, Izmir, Turkey.
Biomark Med. 2019 Feb;13(3):197-204. doi: 10.2217/bmm-2018-0252. Epub 2019 Jan 3.
We aimed to evaluate platelet-to-lymphocyte ratio (PLR) in patients with sarcoidosis.
A total of 310 sarcoidosis patients and 220 healthy controls retrospectively were recorded in this study.
PLR was significantly higher in patients with sarcoidosis than in the control group, and was also significantly higher in patients with pulmonary involvement in stage 2-3-4 than in stage 1. PLR were significantly positive correlated with erythrocyte sedimentation rate. The cut-off values for PLR for predicting a sarcoidosis diagnosis were determined as 158.
Increase in PLR value can be used for guiding both the diagnosis of sarcoidosis and the involvement of parenchyma.
评估结节病患者的血小板与淋巴细胞比值（PLR）。
本研究回顾性记录了 310 例结节病患者和 220 例健康对照者。
与对照组相比，结节病患者的 PLR 显著升高，且 2-3-4 期肺部受累患者的 PLR 也显著高于 1 期患者。PLR 与红细胞沉降率呈显著正相关。预测结节病诊断的 PLR 截断值确定为 158。
PLR 值的升高可用于指导结节病的诊断和实质受累的评估。
