Department of Pulmonology, Health Siences University Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital, Izmir, Turkey.
Sarcoidosis Vasc Diffuse Lung Dis. 2020;37(4):e2020012. doi: 10.36141/svdld.v37i4.9966. Epub 2020 Dec 16.
To evaluate Platelet-to-Lymphocyte Ratio (PLR) and Neutrophil-to-Lymphocyte Ratio (NLR) in patients with HP.
A sample of 140 total patients, 50 having chronic HP and 20 having acute HP, and a control group of 70 more patients were included in this retrospective study conducted with hospital Ethical Committee approval.
PLR and NLR values were significantly higher in all HP patients than in the control group ( p <0.001). In addition, these biomarkers were significantly higher in patients with acute HP than in the chronic HP group (p = 0.017 and p = 0.044, respectively). The cutoff values for PLR and NLR were: (1) 177 (p = 0.020) and 2.76 (p <0.0001) between the HP patients and the control group, and, (2) 110 (p = 0.0054) and 2.15 (p = 0.03), between the acute and chronic HP groups.
PLR and NLR values are inexpensive and easy parameters that can guide in diagnosing hypersensitivity pneumonia in combination with clinical, radiological and pathology findings.and the acute-chronic differentiation of the disease. .
评估血小板与淋巴细胞比值（PLR）和中性粒细胞与淋巴细胞比值（NLR）在 HP 患者中的作用。
本回顾性研究共纳入 140 例患者，其中慢性 HP 患者 50 例，急性 HP 患者 20 例，对照组 70 例，均获得医院伦理委员会批准。
所有 HP 患者的 PLR 和 NLR 值均明显高于对照组（p<0.001）。此外，急性 HP 患者的这些生物标志物明显高于慢性 HP 组（p=0.017 和 p=0.044）。PLR 和 NLR 的截断值为：（1）HP 患者与对照组之间分别为 177（p=0.020）和 2.76（p<0.0001），（2）急性和慢性 HP 组之间分别为 110（p=0.0054）和 2.15（p=0.03）。
PLR 和 NLR 值是廉价且易于获取的参数，与临床、影像学和病理学发现相结合，有助于诊断变应性肺炎，并有助于区分疾病的急慢性。
