Hu Hong, Wang Jing, Zhou Xiao-Yun, Tong Meng-Ting, Zhai Chong-Ya, Sui Xin-Bing, Zhang Yan-Hua, Xie Xiao-Xi, Liu Hao, Xie Jian-Sheng, Pan Hong-Ming, Li Da
Department of Medical Oncology, Xiasha Campus of Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Department of Medical Oncology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Comb Chem High Throughput Screen. 2018;21(10):801-805. doi: 10.2174/1386207322666190103105938.
Esophageal cancer (EC) is a common digestive system tumor, characterized by high invasion, apparent lethality, and poor prognosis. Direct diffusion is the major metastatic mechanism of early EC, whereas advanced EC is spread mainly by lymphatic metastasis, but also can be transferred to the liver, lungs, bones, and so on, by hematogenous metastasis. The incidence of bone metastasis in esophageal cancer is low, and maxillary metastasis of EC is more rare.
To explore the differential diagnosis in ECMM, the rare metastasis of EC, and the possible mechanisms and predictors of bone metastasis.
The clinical materials of a male patient with maxillary metastasis of esophageal cancer (ECMM) were analyzed. Then, the possible mechanism of the ECMM was discussed.
ECMM may belong to the hematogenous metastasis. The early detection of rare sites of metastasis of EC should be prioritized in tumor marker detection, imaging, pathology, and other diagnostic techniques.
食管癌（EC）是一种常见的消化系统肿瘤，具有侵袭性强、致死率高及预后差的特点。直接扩散是早期食管癌的主要转移机制，而晚期食管癌主要通过淋巴转移，也可通过血行转移至肝脏、肺、骨等部位。食管癌骨转移的发生率较低，而上颌骨转移更为罕见。
探讨食管癌上颌骨转移（ECMM）这一罕见的食管癌转移情况的鉴别诊断、骨转移的可能机制及预测因素。
分析1例食管癌上颌骨转移男性患者的临床资料，并探讨ECMM的可能机制。
ECMM可能属于血行转移。在肿瘤标志物检测、影像学、病理学等诊断技术中，应优先早期发现食管癌罕见转移部位。
