Zafar Syed Nabeel, Felton Jessica, Miller Kaylie, Wise Eric S, Kligman Mark
Department of Surgery, University of Maryland Medical Center, Baltimore, Maryland.
School of Medicine, University of Maryland, Baltimore, Maryland.
JSLS. 2018 Oct-Dec;22(4). doi: 10.4293/JSLS.2018.00056.
Staple line treatment during laparoscopic sleeve gastrectomy (LSG) remains a controversial issue among bariatric surgeons. The objective of this study was to compare rates of postoperative bleeding (POB) among various methods of staple line reinforcement.
The Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program 2015 dataset was queried for patients undergoing an LSG. Patients were stratified by staple line treatment groups-no treatment (NT), suture oversewing (OVERSEW), buttressing by a commercial product (BUTTRESS), and both buttress and oversew (COMBINATION). The primary outcome was POB. Multivariable logistic regression was used to compare POB rates among the treatment groups.
In the 98,142 LSG patients meeting selection criteria, 623 (0.63%) patients had POB and 181 (0.18%) required reoperation. POB occurred in 0.80% for the NT group, 0.68% for the OVERSEW group, 0.57% for the BUTTRESS group, and 0.55% for the COMBINATION group. On multivariable analyses, all treatment groups were less likely to have POB compared with the NT group-OVERSEW (odds ratio [OR] 0.73, 95% confidence interval [CI] 0.54-0.98), BUTTRESS (OR 0.70, 95% CI 0.57-0.84), and COMBINATION (OR 0.66, 95% CI 0.50-0.89) (all < .01). Subset analysis revealed no difference between BUTTRESS and OVERSEW (OR 0.95, 95% CI 0.71-1.26, = .71).
Relative to an NT staple line, the use of OVERSEW or BUTTRESS can decrease the rates of POB by up to 30%. The use of these techniques should be strongly considered by the bariatric surgeon.
在腹腔镜袖状胃切除术(LSG)中,吻合钉线处理仍是减重外科医生之间存在争议的问题。本研究的目的是比较各种吻合钉线加固方法的术后出血(POB)发生率。
查询代谢与减重手术认证及质量改进计划2015数据集,以获取接受LSG的患者信息。患者按吻合钉线处理组分层——不处理(NT)、缝合包埋(OVERSEW)、使用商业产品加固(BUTTRESS)以及同时进行加固和包埋(COMBINATION)。主要结局是POB。采用多变量逻辑回归比较各治疗组的POB发生率。
在符合入选标准的98142例LSG患者中,623例(0.63%)发生POB,181例(0.18%)需要再次手术。NT组POB发生率为0.80%,OVERSEW组为0.68%,BUTTRESS组为0.57%,COMBINATION组为0.55%。多变量分析显示,与NT组相比,所有治疗组发生POB的可能性均较小——OVERSEW组(比值比[OR]0.73,95%置信区间[CI]0.54 - 0.98)、BUTTRESS组(OR 0.70,95% CI 0.57 - 0.84)和COMBINATION组(OR 0.66,95% CI 0.50 - 0.89)(均P <.01)。亚组分析显示BUTTRESS组和OVERSEW组之间无差异(OR 0.95,95% CI 0.71 - 1.26,P = 0.71)。
相对于NT吻合钉线,使用OVERSEW或BUTTRESS可使POB发生率降低多达30%。减重外科医生应强烈考虑使用这些技术。