1 Hospital Universitari Vall d'Hebron, Barcelona, Spain.
2 Universitat Autònoma de Barcelona, Bellaterra, Spain.
Clin Rehabil. 2019 Apr;33(4):631-641. doi: 10.1177/0269215518821785. Epub 2019 Jan 4.
: To compare the effectiveness of a precast adjustable compression system with that of multilayered compression bandages in the treatment of breast cancer-related lymphoedema.
: Multicenter, randomized, single-blind parallel-group clinical trial.
: The rehabilitation services of four general university hospitals.
: Patients with upper limb breast cancer-related lymphoedema.
: All the patients received manual lymphatic drainage, followed by a precast adjustable compression system or multilayered compression bandages, according to the group allocation. The treatment included 10 consecutive sessions over a two-week period from Monday to Friday, followed by some sessions on three alternate days per week, until the patient received a tailored compression garment.
: The patients were evaluated just before the treatment, after 10 sessions and at three months posttreatment. The primary outcome was the change in excess lymphoedema volume. Secondary outcomes were changes in the symptoms of pain, heaviness, tightness and hardness. Analyses were performed using an intention-to-treat approach.
: In all, 42 patients were included; there were 22 in the precast adjustable compression system group and 20 in the multilayered compression bandages group. Both groups exhibited significant decreases in excess volume and symptoms after 10 sessions and at three months. There were no significant differences regarding excess volume or symptoms between the precast adjustable compression system and multilayered compression bandages groups after 10 sessions and at the three-month follow-up exam.
: The precast adjustable compression system and the multilayered compression bandages have similar efficacy for the reduction of excess lymphoedema volume or symptoms.
比较预制可调节压缩系统与多层压缩绷带在治疗乳腺癌相关淋巴水肿方面的疗效。
多中心、随机、单盲平行组临床试验。
四所综合大学附属医院的康复服务。
上肢乳腺癌相关淋巴水肿患者。
所有患者均接受手动淋巴引流，然后根据分组使用预制可调节压缩系统或多层压缩绷带。治疗包括 10 次连续治疗，每周一至周五进行，为期两周，然后每周进行 3 次间歇治疗，直到患者接受定制的压缩服。
患者在治疗前、治疗 10 次后和治疗后 3 个月进行评估。主要结局指标为多余淋巴水肿体积的变化。次要结局指标为疼痛、沉重感、紧绷感和硬度等症状的变化。分析采用意向治疗方法。
共有 42 例患者纳入研究，其中预制可调节压缩系统组 22 例，多层压缩绷带组 20 例。两组在 10 次治疗后和 3 个月时，多余体积和症状均显著减少。在 10 次治疗后和 3 个月随访检查时，预制可调节压缩系统组和多层压缩绷带组在多余体积或症状方面均无显著差异。
预制可调节压缩系统和多层压缩绷带在减少多余淋巴水肿体积或症状方面具有相似的疗效。
