用于术后疼痛管理的草药疗法：一项随机对照试验系统评价的方案
Herbal medicine for the management of postoperative pain: A protocol for the systematic review of randomized controlled trials.
作者信息
Park Kyung Moo, Kim Ji Hwan
机构信息
Department of Korean Medicine Rehabilitation.
Department of Sasang Constitutional Medicine, College of Korean Medicine, Gachon University, Seongnam, Korea.
出版信息
Medicine (Baltimore). 2019 Jan;98(1):e14016. doi: 10.1097/MD.0000000000014016.
BACKGROUND
Postoperative pain is caused by surgical trauma and poses a significant challenge for health care providers. Opioid analgesics are commonly used to control postoperative pain. However, these drugs are associated with a number of negative side effects. This review will assess the clinical evidence for and against the use of herbal medicine formulas as a treatment for postoperative pain, especially after musculoskeletal surgery.
METHODS
Twelve databases will be searched from inception to March 2019. We will include randomized controlled trials (RCTs) assessing herbal medicine decoctions used to treat any type of postoperative pain. All RCTs of decoctions or modified decoctions will be included. The methodologic qualities of the RCTs will be assessed using the Cochrane Collaboration tool for assessing risk of bias, while confidence in the cumulative evidence will be evaluated using the Grading of Recommendations Assessment, Development, and Evaluation method.
CONCLUSION
This systematic review will be published in a peer-reviewed journal and disseminated electronically and in print. The review will be updated to inform and guide health care practices.Registration number: CRD42018094897.
背景
术后疼痛由手术创伤引起，对医疗服务提供者构成重大挑战。阿片类镇痛药常用于控制术后疼痛。然而，这些药物会带来许多负面副作用。本综述将评估支持和反对使用草药配方治疗术后疼痛，尤其是肌肉骨骼手术后疼痛的临床证据。
方法
将检索12个数据库，检索时间从建库至2019年3月。我们将纳入评估用于治疗任何类型术后疼痛的草药汤剂的随机对照试验（RCT）。所有汤剂或改良汤剂的RCT均将纳入。将使用Cochrane协作网评估偏倚风险的工具评估RCT的方法学质量，同时使用推荐分级评估、制定与评价方法评估对累积证据的信心。
结论
本系统综述将发表在同行评审期刊上，并以电子和印刷形式传播。该综述将更新，以为医疗实践提供信息和指导。注册号：CRD42018094897。
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