Rex J H, Ginsberg A M, Fries L F, Pass H I, Kwon-Chung K J
Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892.
Rev Infect Dis. 1988 Nov-Dec;10(6):1187-94. doi: 10.1093/clinids/10.6.1187.
Cunninghamella bertholletiae, an uncommon cause of human infection, has been reported with increasing frequency in recent years. C. bertholletiae belongs to the order Mucorales and produces infections similar to those produced by the other agents of mucormycosis. Infections with this group of organisms have typically been seen either in patients with diabetes mellitus or in those receiving chemotherapy. Recent reports of mucormycosis in dialysis patients receiving deferoxamine for iron or aluminum overload have raised the possibility that deferoxamine therapy is a risk factor for mucormycosis. A case of C. bertholletiae infection in a patient receiving deferoxamine for iron overload unrelated to hemodialysis was investigated in detail, and possible explanations for this patient's infection were assessed.
伯氏小克银汉霉是一种罕见的人类感染病原体，近年来其报告发病率呈上升趋势。伯氏小克银汉霉属于毛霉目，可引发与其他毛霉菌病病原体相似的感染。这类生物体感染通常见于糖尿病患者或接受化疗的患者。近期有报告称，接受去铁胺治疗以应对铁或铝过载的透析患者发生了毛霉菌病，这增加了去铁胺治疗是毛霉菌病危险因素的可能性。对一名因铁过载接受去铁胺治疗且与血液透析无关的患者发生的伯氏小克银汉霉感染病例进行了详细调查，并评估了该患者感染的可能原因。
