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Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.尼日利亚前列腺癌 Transatlantic 联盟（CaPTC）肿瘤的全外显子组测序揭示了与非洲血统相关的 DNA 修复基因。
Cancer Res Commun. 2022 Sep 16;2(9):1005-1016. doi: 10.1158/2767-9764.CRC-22-0136. eCollection 2022 Sep.
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Review of prostate cancer genomic studies in Africa.非洲前列腺癌基因组研究综述。
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TMPRSS2-ERG fusions linked to prostate cancer racial health disparities: A focus on Africa.TMPRSS2-ERG 融合与前列腺癌的种族健康差异有关：以非洲为例。
Prostate. 2019 Jul;79(10):1191-1196. doi: 10.1002/pros.23823. Epub 2019 May 15.

本文引用的文献

1
Prostate Cancer in Southern Africa: Does Africa Hold Untapped Potential to Add Value to the Current Understanding of a Common Disease?非洲南部的前列腺癌：非洲对于增进当前对这种常见疾病的认识是否具有尚未开发的潜力？
J Glob Oncol. 2018 Sep;4:1-7. doi: 10.1200/JGO.2016.008862. Epub 2017 Mar 21.
2
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.对前列腺癌的测序鉴定出了新的癌症基因、进展途径和药物靶点。
Nat Genet. 2018 May;50(5):682-692. doi: 10.1038/s41588-018-0086-z. Epub 2018 Apr 16.
3
Tumor Mutational Burden as an Independent Predictor of Response to Immunotherapy in Diverse Cancers.肿瘤突变负荷作为预测多种癌症免疫治疗反应的独立标志物。
Mol Cancer Ther. 2017 Nov;16(11):2598-2608. doi: 10.1158/1535-7163.MCT-17-0386. Epub 2017 Aug 23.
4
Genomic hallmarks of localized, non-indolent prostate cancer.局限性、非惰性前列腺癌的基因组特征。
Nature. 2017 Jan 19;541(7637):359-364. doi: 10.1038/nature20788. Epub 2017 Jan 9.
5
Mutational Landscape of Aggressive Prostate Tumors in African American Men.非裔美国男性侵袭性前列腺肿瘤的突变图谱
Cancer Res. 2016 Apr 1;76(7):1860-8. doi: 10.1158/0008-5472.CAN-15-1787. Epub 2016 Feb 26.
6
Familial Risk and Heritability of Cancer Among Twins in Nordic Countries.北欧国家双胞胎中癌症的家族风险与遗传度。
JAMA. 2016 Jan 5;315(1):68-76. doi: 10.1001/jama.2015.17703.
7
Clinical presentation of prostate cancer in black South Africans.黑人南非人群中前列腺癌的临床表现。
Prostate. 2014 Jun;74(8):880-91. doi: 10.1002/pros.22806. Epub 2014 Apr 9.
8
Cancer statistics, 2014.癌症统计数据，2014 年。
CA Cancer J Clin. 2014 Jan-Feb;64(1):9-29. doi: 10.3322/caac.21208. Epub 2014 Jan 7.
9
Addressing the contribution of previously described genetic and epidemiological risk factors associated with increased prostate cancer risk and aggressive disease within men from South Africa.探讨先前描述的遗传和流行病学风险因素在南非男性中与前列腺癌风险增加和侵袭性疾病的关系。
BMC Urol. 2013 Dec 29;13:74. doi: 10.1186/1471-2490-13-74.
10
Mutational heterogeneity in cancer and the search for new cancer-associated genes.癌症中的突变异质性与新的癌症相关基因的寻找。
Nature. 2013 Jul 11;499(7457):214-218. doi: 10.1038/nature12213. Epub 2013 Jun 16.

Prostate cancer genomics and racial health disparity.

作者信息

Hayes Vanessa M, Jaratlerdsiri Weerachai, Bornman M S Riana

机构信息

Laboratory for Human Comparative and Prostate Cancer Genomics, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia; St Vincent's Clinical School, University of New South Wales, Randwick, NSW, Australia; Central Clinical School, University of Sydney, Camperdown, NSW, Australia; School of Health Systems and Public Health, University of Pretoria, Pretoria, South Africa.

出版信息

Oncotarget. 2018 Nov 30;9(94):36650-36651. doi: 10.18632/oncotarget.26399.

DOI:10.18632/oncotarget.26399
PMID:30613347
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6291177/
Abstract
摘要