3rd Department of Neurology, Aristotle University of Thessaloniki, G. Papanikolaou Hospital, Thessaloniki, Greece.
Laboratory of Primary Health Care, General Practice and Health Services Research - Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Neurol Sci. 2019 Apr;40(4):683-690. doi: 10.1007/s10072-018-3695-5. Epub 2019 Jan 8.
Fatigue is one of the most frequent and important nonmotor symptoms of patients with Parkinson disease (PD), affecting quality of life. Although, in some cases, it may be a severe and debilitating complaint, it remains relatively unexplored. The PFS-16 is a fatigue measure, specifically designed for PD patients. The aim of this study was to investigate the psychometric properties of Parkinson fatigue scale (PFS-16) in Greek PD patients.
In total, 99 patients with PD were assessed. The following psychometric properties were tested: data quality, floor/ceiling effects, reliability (internal consistency, test-retest reliability), and construct validity. Construct validity was evaluated by examining correlations with other variables including other fatigue measures such as Fatigue Severity Scale (FSS) and the vitality scale (SF-VT) of SF-36. Moreover, assumptions were explored about "known" groups concerning fatigue.
The mean score for the PFS-16 was 2.95 (± 0.91); acceptability was good with negligible floor and ceiling effects. Results showed high internal consistency (Cronbach's alpha, 0.96) and test-retest reliability (ICC, 0.93). Strong correlations were observed between the PFS-16 and other fatigue (FFS and SF-VT) measures (rs = 0.77 and - 0.70, p < 0.001), revealing appropriate validity. Furthermore, predictions for "known" groups validity were verified.
The Greek version of the PFS-16 showed satisfactory reliability and validity and thus can be regarded as a useful tool in assessing fatigue in PD.
疲劳是帕金森病（PD）患者最常见和最重要的非运动症状之一，影响生活质量。虽然在某些情况下，它可能是一种严重且使人虚弱的主诉，但对其的研究仍相对较少。疲劳严重度量表（PFS-16）是一种专门为 PD 患者设计的疲劳测量工具。本研究旨在调查希腊 PD 患者帕金森疲劳量表（PFS-16）的心理测量特性。
共评估了 99 名 PD 患者。测试了以下心理测量特性：数据质量、地板/天花板效应、可靠性（内部一致性、重测信度）和结构有效性。通过检查与其他变量（包括其他疲劳测量工具，如疲劳严重度量表（FSS）和 SF-36 的活力量表（SF-VT））的相关性来评估结构有效性。此外，还探讨了关于疲劳的“已知”组的假设。
PFS-16 的平均得分为 2.95（±0.91）；可接受性良好，地板和天花板效应可忽略不计。结果显示出较高的内部一致性（Cronbach's alpha，0.96）和重测信度（ICC，0.93）。PFS-16 与其他疲劳（FFS 和 SF-VT）测量之间存在强烈相关性（rs=0.77 和-0.70，p<0.001），表明具有适当的有效性。此外，还验证了对“已知”组有效性的预测。
希腊语版 PFS-16 显示出令人满意的可靠性和有效性，因此可被视为评估 PD 患者疲劳的有用工具。
