Department of Neurosciences and Rehabilitation Tampere University Hospital Tampere Finland.
Finnish Neuro Society Masku Finland.
Brain Behav. 2017 Jun 9;7(7):e00743. doi: 10.1002/brb3.743. eCollection 2017 Jul.
Fatigue is one of the most debilitating symptoms in multiple sclerosis (MS) considerably interfering with patients' daily functioning. Both researchers and clinicians need psychometrically robust methods to evaluate fatigue in MS.
The objective of this study was (i) to evaluate the psychometric properties of the Finnish version of the Fatigue Severity Scale (FSS) and (ii) to describe the results among patients with MS.
In total, 553 patients with MS (mean age, 53.8 years; standard deviation [], 11.4; 79% women: mean patient-defined disease severity, Expanded Disability Status Scale [EDSS] 4.0, , 2.5) completed the self-administered questionnaires including the FSS. A standard procedure was used for the translation of the FSS.
The mean () score for the FSS was 4.5 (1.7); in 65% of the patients, the score was ≥4.0. The data quality of the FSS was excellent, with 99.6% of computable scale scores. Floor and ceiling effects were minimal. The FSS showed high internal consistency (Cronbach's alpha, 0.95). Unidimensionality was supported based on confirmatory factor analysis with the comparative fit index being 0.94. The FSS showed moderate/high correlations with the perceived burden of the disease, quality of life and disease severity, whereas, age or gender did not have a significant effect on the FSS score.
The Finnish version of the FSS showed satisfactory reliability and validity and thus can be regarded as a feasible measure of self-reported fatigue.
疲劳是多发性硬化症（MS）中最令人虚弱的症状之一，极大地影响了患者的日常功能。研究人员和临床医生都需要具有心理测量学可靠性的方法来评估 MS 患者的疲劳。
本研究的目的是（i）评估芬兰版疲劳严重度量表（FSS）的心理测量学特性，（ii）描述 MS 患者的结果。
共有 553 名 MS 患者（平均年龄 53.8 岁，标准差 [] 11.4，79%为女性：平均患者定义的疾病严重程度，扩展残疾状态量表 [EDSS] 4.0，，2.5）完成了包括 FSS 在内的自我管理问卷。采用标准程序对 FSS 进行翻译。
FSS 的平均（）得分为 4.5（1.7）；在 65%的患者中，得分≥4.0。FSS 的数据质量极佳，可计算的量表得分占 99.6%。地板和天花板效应最小。FSS 显示出较高的内部一致性（Cronbach's alpha，0.95）。基于验证性因子分析，支持单维性，比较拟合指数为 0.94。FSS 与疾病负担、生活质量和疾病严重程度的感知呈中度/高度相关性，而年龄或性别对 FSS 评分没有显著影响。
芬兰版 FSS 显示出令人满意的可靠性和有效性，因此可以被视为一种可行的自我报告疲劳测量方法。
