帕金森病中的疲劳：多学科研讨会报告
Fatigue in Parkinson's disease: report from a mutidisciplinary symposium.
作者信息
Friedman Joseph H, Beck James C, Chou Kelvin L, Clark Gracia, Fagundes Christopher P, Goetz Christopher G, Herlofson Karen, Kluger Benzi, Krupp Lauren B, Lang Anthony E, Lou Jao-Shin, Marsh Laura, Newbould Anne, Weintraub Daniel
机构信息
Movement Disorders Program, Butler Hospital, Province, RI, USA; Department of Neurology, Alpert Medical School of Brown University, Providence, RI, USA.
Parkinson's Disease Foundation, New York, NY, USA.
出版信息
NPJ Parkinsons Dis. 2016;2:15025-. doi: 10.1038/npjparkd.2015.25. Epub 2016 Jan 14.
Fatigue is a severe problem for many people living with Parkinson's disease (PD). Best estimates suggest that more than 50% of patients experience this debilitating symptom. Little is known about its etiology or treatment, making the understanding of fatigue a true unmet need. As part of the Parkinson's Disease Foundation Community Choice Research Program, patients, caregivers, and scientists attended a symposium on fatigue on 16 and 17 October 2014. We present a summary of that meeting, reviewing what is known about the diagnosis and treatment of fatigue, its physiology, and what we might learn from multiple sclerosis (MS), depression, and cancer-disorders in which fatigue figures prominently too. We conclude with focused recommendations to enhance our understanding and treatment of this prominent problem in PD.
疲劳是许多帕金森病（PD）患者面临的严重问题。据最佳估计，超过50%的患者会出现这种使人衰弱的症状。人们对其病因或治疗方法知之甚少，这使得对疲劳的了解成为一个真正未得到满足的需求。作为帕金森病基金会社区选择研究项目的一部分，患者、护理人员和科学家于2014年10月16日和17日参加了一次关于疲劳的研讨会。我们在此呈现该会议的总结，回顾关于疲劳的诊断和治疗、其生理学的已知情况，以及我们可能从多发性硬化症（MS）、抑郁症和癌症等疾病中学到的东西——在这些疾病中疲劳也很突出。我们最后提出重点建议，以加强我们对帕金森病中这一突出问题的理解和治疗。
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