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[影像学在上尿路肿瘤中的价值]

[Value of imaging in upper urinary tract tumors].

作者信息

Schulz G B, Gresser E K, Casuscelli J, Strittmatter F, Tritschler S, Karl A, Stief C G, Nörenberg D

机构信息

Urologische Klinik und Poliklinik, Klinikum der Universität München, Campus Großhadern, Marchioninistr. 15, 81377, München, Deutschland.

Klinik und Poliklinik für Radiologie, Klinikum der Universität München, Campus Großhadern, München, Deutschland.

出版信息

Urologe A. 2019 Jan;58(1):5-13. doi: 10.1007/s00120-018-0828-7.

DOI:10.1007/s00120-018-0828-7
PMID:30617530
Abstract

BACKGROUND

Staging of bladder cancer, hematuria as well as the evaluation of unclear findings of the kidneys and ureters are the most frequent indications for imaging of the upper urinary tract (UUT). Endourological assessment of the UUT is much more invasive compared to imaging of the bladder, raising the question of the optimal imaging technique. Several technical improvements regarding computed tomography (CT) as well as magnetic resonance imaging (MRI) were implemented in recent years.

OBJECTIVES

To compare the efficacy and limitations of the most important imaging techniques regarding the UUT.

MATERIALS AND METHODS

Systematic review of the literature and current German, European, and American guidelines regarding bladder cancer, urothelial carcinoma of the UUT and hematuria.

RESULTS

The CT-based urography has superseded excretory urography and is the first choice for imaging of the UUT. In case of contraindications, MRI is a feasible alternative. In all cases, a urography phase is indispensable.

CONCLUSIONS

Imaging of the UUT has to be used in a reasonable combination together with endourological methods and cytology. Optical coherence tomography, confocal laser endomicroscopy and scientific innovations such as radiomics might improve UUT imaging and differential diagnosis of UUT lesions in the future.

摘要

背景

膀胱癌分期、血尿以及对肾脏和输尿管不明病变的评估是上尿路(UUT)成像最常见的指征。与膀胱成像相比,UUT的腔内泌尿外科评估侵入性更强,这就引发了关于最佳成像技术的问题。近年来,计算机断层扫描(CT)和磁共振成像(MRI)在技术上有了多项改进。

目的

比较UUT最重要成像技术的有效性和局限性。

材料与方法

对关于膀胱癌、UUT尿路上皮癌和血尿的文献以及当前德国、欧洲和美国的指南进行系统综述。

结果

基于CT的尿路造影已取代排泄性尿路造影,是UUT成像的首选。如有禁忌证,MRI是一种可行的替代方法。在所有情况下,尿路造影期都是必不可少的。

结论

UUT成像必须与腔内泌尿外科方法和细胞学合理结合使用。光学相干断层扫描、共聚焦激光内镜显微镜以及诸如放射组学等科学创新未来可能会改善UUT成像和UUT病变的鉴别诊断。

相似文献

1
[Value of imaging in upper urinary tract tumors].[影像学在上尿路肿瘤中的价值]
Urologe A. 2019 Jan;58(1):5-13. doi: 10.1007/s00120-018-0828-7.
2
CT urography for hematuria.CT 尿路造影检查用于血尿。
Nat Rev Urol. 2012 Mar 13;9(4):218-26. doi: 10.1038/nrurol.2012.32.
3
Computed tomography-urography for upper urinary tract imaging: is it required for all patients who present with hematuria?计算机断层尿路造影对上尿路成像:所有血尿患者都需要做吗?
J Endourol. 2011 Nov;25(11):1733-40. doi: 10.1089/end.2011.0225. Epub 2011 Aug 18.
4
Optical diagnostics for upper urinary tract urothelial cancer: technology, thresholds, and clinical applications.上尿路尿路上皮癌的光学诊断:技术、阈值及临床应用
J Endourol. 2015 Feb;29(2):113-23. doi: 10.1089/end.2014.0551. Epub 2014 Oct 16.
5
Clinical staging of upper urinary tract urothelial carcinoma for T staging: Review and pictorial essay.上尿路尿路上皮癌 T 分期的临床分期:综述与影像学评价。
Int J Urol. 2019 Nov;26(11):1024-1032. doi: 10.1111/iju.14068. Epub 2019 Aug 4.
6
Poor visualization of renal collecting system in intravenous urography as an indicator of invasive transitional cell carcinoma in the upper urinary tract.静脉尿路造影中肾集合系统显影不佳作为上尿路浸润性移行细胞癌的一个指标。
Chin Med J (Engl). 2007 Aug 20;120(16):1387-90.
7
Volumetric in vivo visualization of upper urinary tract tumors using optical coherence tomography: a pilot study.光学相干断层扫描对上尿路肿瘤的容积体内可视化:一项初步研究。
J Urol. 2013 Dec;190(6):2236-42. doi: 10.1016/j.juro.2013.08.006. Epub 2013 Aug 13.
8
[Clinical, ureteroscopic and photodynamic diagnosis of urothelial carcinomas of the upper tract: state-of-the art review for the yearly scientific report of the French National Association of Urology].[上尿路尿路上皮癌的临床、输尿管镜及光动力诊断:法国国家泌尿外科学会年度科学报告的最新综述]
Prog Urol. 2014 Nov;24(15):977-86. doi: 10.1016/j.purol.2014.07.012. Epub 2014 Sep 8.
9
Upper urinary tract urothelial carcinoma on multidetector CT: spectrum of disease.多排螺旋 CT 尿路上皮癌:疾病谱。
Abdom Radiol (NY). 2019 Dec;44(12):3874-3885. doi: 10.1007/s00261-019-02173-2.
10
Multidetector computerized tomography urography is more accurate than excretory urography for diagnosing transitional cell carcinoma of the upper urinary tract in adults with hematuria.多排计算机断层尿路造影术比排泄性尿路造影术更准确,可用于诊断血尿成人上尿路移行细胞癌。
J Urol. 2010 Jan;183(1):48-55. doi: 10.1016/j.juro.2009.08.144.

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Mol Biol Rep. 2023 Oct;50(10):8297-8304. doi: 10.1007/s11033-023-08667-z. Epub 2023 Aug 17.
2
Conservative Treatment of Upper Urinary Tract Urothelial Carcinoma: Con.上尿路尿路上皮癌的保守治疗:结论
Eur Urol Open Sci. 2021 Sep 6;32:35-37. doi: 10.1016/j.euros.2021.08.003. eCollection 2021 Oct.
3
Guideline of guidelines: Muscle-invasive bladder cancer.指南之指南:肌层浸润性膀胱癌

本文引用的文献

1
Computed Tomography Urography: Comparison of Image Quality and Radiation Dose between Single- and Split-Bolus Techniques.计算机断层尿路造影术:单次和分次团注技术的图像质量和辐射剂量比较。
Ann Acad Med Singap. 2018 Aug;47(8):278-284.
2
Performance of diffusion-weighted MRI post-CT urography for the diagnosis of upper tract urothelial carcinoma: Comparison with selective urine cytology sampling.CT尿路造影术后扩散加权磁共振成像在上尿路尿路上皮癌诊断中的应用:与选择性尿液细胞学采样的比较
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Development and Validation of an MRI-Based Radiomics Signature for the Preoperative Prediction of Lymph Node Metastasis in Bladder Cancer.
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[Follow-up surveillance of muscle-invasive urinary bladder cancer after curative treatment].[根治性治疗后肌肉浸润性膀胱癌的随访监测]
Urologe A. 2019 Sep;58(9):1093-1106. doi: 10.1007/s00120-019-1012-4.
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[Aftercare of non-muscle invasive bladder cancer].[非肌层浸润性膀胱癌的术后护理]
Urologe A. 2019 Aug;58(8):943-952. doi: 10.1007/s00120-019-0956-8.
基于 MRI 的影像组学signature 用于膀胱癌术前预测淋巴结转移的建立与验证
EBioMedicine. 2018 Aug;34:76-84. doi: 10.1016/j.ebiom.2018.07.029. Epub 2018 Aug 2.
4
Upper and Lower Tract Urothelial Imaging Using Computed Tomography Urography.使用计算机断层扫描尿路造影术进行上尿路和下尿路尿路上皮成像
Urol Clin North Am. 2018 Aug;45(3):389-405. doi: 10.1016/j.ucl.2018.03.004.
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Can Renal and Bladder Ultrasound Replace Computerized Tomography Urogram in Patients Investigated for Microscopic Hematuria?肾脏和膀胱超声检查能否替代计算机断层尿路造影检查用于显微镜下血尿患者的检查?
J Urol. 2018 Nov;200(5):973-980. doi: 10.1016/j.juro.2018.04.065. Epub 2018 Apr 24.
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Upper tract urothelial cancer.上尿路尿路上皮癌。
Eur J Radiol. 2018 Jan;98:50-60. doi: 10.1016/j.ejrad.2017.10.021. Epub 2017 Nov 8.
7
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2017 Update.欧洲泌尿外科学会上尿路尿路上皮癌指南:2017 年更新版。
Eur Urol. 2018 Jan;73(1):111-122. doi: 10.1016/j.eururo.2017.07.036. Epub 2017 Sep 1.
8
Bladder Cancer Treatment Response Assessment in CT using Radiomics with Deep-Learning.基于深度学习的 CT 影像组学膀胱癌治疗反应评估
Sci Rep. 2017 Aug 18;7(1):8738. doi: 10.1038/s41598-017-09315-w.
9
Upper Urinary Tract Tumors: Which Diagnostic Methods Are Needed?上尿路肿瘤:需要哪些诊断方法?
Urol Int. 2017;98(3):304-311. doi: 10.1159/000457133. Epub 2017 Feb 28.
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Role of Imaging in the Local Staging of Urothelial Carcinoma of the Bladder.影像学在膀胱尿路上皮癌局部分期中的作用
AJR Am J Roentgenol. 2017 Jun;208(6):1193-1205. doi: 10.2214/AJR.16.17114. Epub 2017 Feb 22.