Zhang Jie, Sun Jian, Chen Xiyue, Nie Cunxi, Zhao Jinbiao, Guan Wenyi, Lei Lihui, He Ting, Chen Yiqiang, Johnston Lee J, Zhao Jinshan, Ma Xi
State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Department of Animal Husbandry and Veterinary, Beijing Vocational College of Agriculture, Beijing, China.
Front Microbiol. 2018 Dec 18;9:3091. doi: 10.3389/fmicb.2018.03091. eCollection 2018.
Experimental manipulation of the intestinal microbiota influences health of the host and is a common application for synbiotics. Here (, ) combined with corn bran ( + Bran) was taken as the synbiotics application in a waned pig model to investigate its regulation of intestinal health over 28 days postweaning. Growth performance, fecal short chain fatty acids (SCFAs) and bacterial community were evaluated at day 14 and day 28 of the trial. Although the + Bran treatment has no significant effects on growth performance ( > 0.05), it optimized the composition of intestinal bacteria, mainly represented by increased acetate-producing bacteria and decreased pathogens. Microbial fermentation in the intestine showed a shift from low acetate and isovalerate production on day 14 to enhanced acetate production on day 28 in the + Bran treatment. Thus, and corn bran promoted intestinal microbial fermentation and optimized the microbial community for pigs at an early age. These findings provide perspectives on the advantages of synbiotics as a new approach for effective utilization of corn barn.
对肠道微生物群进行实验性调控会影响宿主健康，这是合生元的常见应用。在此，（此处原文括号内容缺失信息无法准确翻译）与玉米麸皮（+麸皮）组合被用作断奶仔猪模型中的合生元应用，以研究其在断奶后28天内对肠道健康的调节作用。在试验的第14天和第28天评估生长性能、粪便短链脂肪酸（SCFAs）和细菌群落。尽管+麸皮处理对生长性能没有显著影响（P>0.05），但它优化了肠道细菌的组成，主要表现为产乙酸细菌增加和病原体减少。在+麸皮处理中，肠道微生物发酵显示出从第14天乙酸和异戊酸产量低到第28天乙酸产量增加的转变。因此，（此处原文缺失内容无法准确翻译）和玉米麸皮促进了早期仔猪的肠道微生物发酵并优化了微生物群落。这些发现为合生元作为有效利用玉米麸的新方法的优势提供了见解。
