Corbishley C M, Saverymuttu S H, Maxwell J D
Department of Histopathology, St George's Hospital Medical School, London.
J Clin Pathol. 1988 Nov;41(11):1187-90. doi: 10.1136/jcp.41.11.1187.
The specificity of endoscopic biopsy specimens in diagnosing congestive gastropathy in 20 patients with portal hypertension, 20 patients with liver disease without portal hypertension, and 20 patients with a normal stomach at endoscopy without liver disease was examined. Histological assessment, which was performed without knowledge of the clinical details, showed changes previously reported to be indicative of congestive gastropathy in 9 (47%) of patients with portal hypertension. Similar changes were also seen in 17 (85%) of patients with liver disease without portal hypertension and in 16 (84%) of patients with normal endoscopies without liver disease. These results show that the histological changes seen in endoscopic biopsy specimens of congestive gastropathy are not specific for this condition and therefore cannot be used to diagnose objectively the disease or assess management.
对20例门静脉高压患者、20例无门静脉高压的肝病患者以及20例内镜检查显示胃正常且无肝病的患者的内镜活检标本在诊断充血性胃病方面的特异性进行了检查。在不知道临床细节的情况下进行的组织学评估显示，9例（47%）门静脉高压患者出现了先前报道的提示充血性胃病的变化。在17例（85%）无门静脉高压的肝病患者和16例（84%）内镜检查正常且无肝病的患者中也观察到了类似变化。这些结果表明，充血性胃病内镜活检标本中所见的组织学变化并非该疾病所特有，因此不能用于客观诊断该疾病或评估治疗。
