School of Medicine, Stony Brook University, Stony Brook, NY, USA.
Department of Orthopaedics, Stony Brook University Medical Center, HSC T-18, Room 080, Stony Brook, NY, 11794-8181, USA.
J Orthop Surg Res. 2019 Jan 8;14(1):9. doi: 10.1186/s13018-018-1051-3.
With the increasing elderly population and obesity epidemic, diabetes is an important factor in arthroplasty planning. Although research suggests diabetes is associated with increased postoperative morbidity after hip and knee replacement, the effect of diabetes and varying management with insulin versus non-insulin agents on total shoulder arthroplasty (TSA) is not established.
All TSAs from 2015 to 2016 were queried from the American College of Surgeons National Surgical Quality Improvement Program database. Age, gender, BMI, steroid, ASA, operative time, and smoking status were compared between all diabetics, diabetics on insulin, diabetics on non-insulin agents, and non-diabetics to account for confounding variables. Thirty-day postoperative complications, readmission rate, surgical site infection (SSI), and non-routine discharge to rehabilitation were compared using bivariate and multivariate binary logistic regression. Postoperative time to discharge between diabetic groups was analyzed using univariate ANOVA with Tukey's test.
The analysis included 7246 patients (insulin in 5% (n = 380), non-insulin in 13% (n = 922), and non-diabetics in 82% (n = 5944)). Diabetics were more likely to have an ASA ≥ 3 compared to non-diabetics (89.5% vs 50.1%; p < 0.001). Bivariate logistic regression showed statistical significance in readmission and non-routine discharge between all diabetics and non-diabetics (OR 1.7, 1.4; p = 0.001, 0.001), but there was no significance between SSI rate (0.3% vs 0.4%; p = 0.924). Multivariate logistic regression between groups showed significance in readmission between non-insulin diabetics vs non-diabetics (OR 1.5; p = 0.027), readmission and non-routine discharge in insulin vs non-diabetics (OR 2.1, 1.7; p = 0.003, < 0.001), and no significance between insulin and non-insulin diabetics. Postoperative days to discharge were 2.4, 2.0, and 1.8 days in insulin, non-insulin, and non-diabetics respectively. Mean differences were significant between all groups.
Diabetic patients are at a higher risk for readmission and non-routine discharge compared to non-diabetics. Despite no increased risk in SSI, longer postoperative discharge time in diabetics should be considered in TSA planning.
Not applicable LEVEL OF EVIDENCE: Level III, case-control study.
随着老年人口和肥胖症的增加,糖尿病是关节置换术规划中的一个重要因素。尽管有研究表明,糖尿病与髋关节和膝关节置换术后的高术后发病率有关,但糖尿病的影响以及胰岛素与非胰岛素药物治疗对全肩关节置换术(TSA)的影响尚不确定。
从美国外科医师学院国家手术质量改进计划数据库中查询了 2015 年至 2016 年的所有 TSA。对所有糖尿病患者、胰岛素治疗的糖尿病患者、非胰岛素治疗的糖尿病患者和非糖尿病患者的年龄、性别、BMI、类固醇、ASA、手术时间和吸烟状况进行比较,以考虑混杂因素。使用二变量和多变量二元逻辑回归比较 30 天术后并发症、再入院率、手术部位感染(SSI)和非常规康复出院。使用单变量 ANOVA 和 Tukey 检验分析糖尿病组之间的术后出院时间。
分析包括 7246 例患者(胰岛素占 5%(n=380),非胰岛素占 13%(n=922),非糖尿病占 82%(n=5944))。与非糖尿病患者相比,糖尿病患者的 ASA ≥3 的可能性更大(89.5% vs 50.1%;p<0.001)。二变量逻辑回归显示,所有糖尿病患者与非糖尿病患者之间的再入院率和非常规出院率存在统计学意义(OR 1.7,1.4;p=0.001,0.001),但 SSI 率(0.3% vs 0.4%;p=0.924)无统计学意义。组间多变量逻辑回归显示,非胰岛素糖尿病患者与非糖尿病患者之间的再入院率存在统计学意义(OR 1.5;p=0.027),胰岛素与非糖尿病患者之间的再入院率和非常规出院率存在统计学意义(OR 2.1,1.7;p=0.003,<0.001),而胰岛素与非胰岛素糖尿病患者之间无统计学意义。胰岛素、非胰岛素和非糖尿病患者的术后出院天数分别为 2.4、2.0 和 1.8 天。各组之间的平均差异有统计学意义。
与非糖尿病患者相比,糖尿病患者再入院和非常规出院的风险更高。尽管 SSI 风险没有增加,但在 TSA 计划中应考虑糖尿病患者术后出院时间延长的问题。
不适用 证据水平:三级,病例对照研究。