Faculty of Dentistry, Federal University of Pelotas, Pelotas, Brazil.
Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Pelotas, Pelotas, Brazil.
Biomed Res Int. 2018 Nov 27;2018:8063262. doi: 10.1155/2018/8063262. eCollection 2018.
Mineral Trioxide Aggregate (MTA) is a tricalcium-based silicate, dicalcium silicate matrix. Despite its good biologic properties, some clinicians still claim to have difficulties in handling MTA after its preparation due to its sandy consistency. The aim of the present study was to evaluate the physicochemical properties and cytotoxicity of MTA Repair HP (Angelus, Londrina, PR, Brazil) compared with MTA Angelus (Angelus, Londrina, PR, Brazil).
The properties assessed were particle size, setting time, flow, film thickness, radiopacity, water solubility, compressive strength, and cytotoxicity. Statistical analysis was performed considering p < 0.05 as statistically significant.
For radiopacity, water absorption and solubility MTA Repair HP were statistically similar to MTA Angelus. The MTA Angelus had statistically different film thickness values, higher than MTA Repair HP (p < 0.05). Besides, MTA Angelus showed a lower and statistically different compressive strength after 28 days than MTA Repair HP (p<0.05). Additionally, MTA Repair HP set more slowly (p < 0.05). Relative to cell viability, MTA Repair HP was statistically similar to MTA Angelus after 24 and 48 h in cell viability.
The MTA Repair HP presented similar cell viability, lower film thickness, higher flow, setting time, and compressive strength values after 28 days than MTA Angelus. In general, the MTA Repair HP presented physicochemical and biological properties similar to the MTA Angelus.
矿物三氧化物聚合体(MTA)是一种硅酸三钙基、硅酸二钙基质。尽管其具有良好的生物学特性,但一些临床医生仍声称在准备 MTA 后,由于其沙质的稠度,在操作上存在困难。本研究旨在评估 MTA Repair HP(Angelus,Londrina,PR,巴西)与 MTA Angelus(Angelus,Londrina,PR,巴西)相比的理化性能和细胞毒性。
评估的性能包括粒径、凝固时间、流动性、薄膜厚度、射线不透性、水溶性、抗压强度和细胞毒性。统计分析考虑 p<0.05 为统计学显著。
在射线不透性、吸水性和溶解性方面,MTA Repair HP 与 MTA Angelus 统计学上相似。MTA Angelus 的薄膜厚度值有统计学差异,高于 MTA Repair HP(p<0.05)。此外,MTA Angelus 在 28 天后的抗压强度明显低于 MTA Repair HP(p<0.05)。此外,MTA Repair HP 的凝固时间更慢(p<0.05)。与细胞活力相比,MTA Repair HP 在细胞活力 24 和 48 小时后与 MTA Angelus 统计学相似。
MTA Repair HP 的细胞活力与 MTA Angelus 相似,薄膜厚度较低,流动性较高,凝固时间和 28 天后的抗压强度值较高。一般来说,MTA Repair HP 的理化和生物学性能与 MTA Angelus 相似。