Zhu Chenxi, Ju Bin, Ni Rong
Research Center, Zhejiang Provincial Health Information Center Hangzhou, Zhejiang, China.
Int J Clin Exp Med. 2015 Oct 15;8(10):17055-60. eCollection 2015.
Direct pulp capping is one of the most common dental practices in endodontic therapy. This systematic review and meta-analysis aim to determine whether the effect of mineral trioxide aggregate (MTA) and calcium hydroxide for direct pulp capping is different, as measured by the clinical and radiographic analysis. The study list was obtained by searching PubMed, Springer Link, Scopus and Cochrane Database. Only those papers that met the inclusion criteria were analyzed. The results indicated that four studies met the inclusion criteria. Statistically significant difference was found between the success rates of MTA and calcium hydroxide treated teeth that needed direct pulp capping (P=0.002). Clinical assessments of the MTA versus calcium hydroxide for direct pulp capping suggested that MTA was superior to calcium hydroxide in direct pulp capping resulting in a lower failure rate (risk difference 0.1 [95% CI 0.04 to 0.16]). In conclusion, MTA has a higher clinical success rate for direct pulp capping comparing to calcium hydroxide, and might be a suitable replacement for calcium hydroxide.
直接盖髓术是牙髓病治疗中最常见的牙科治疗方法之一。本系统评价和荟萃分析旨在通过临床和影像学分析确定三氧化矿物凝聚体（MTA）和氢氧化钙用于直接盖髓的效果是否存在差异。通过检索PubMed、Springer Link、Scopus和Cochrane数据库获取研究列表。仅对符合纳入标准的论文进行分析。结果表明，有四项研究符合纳入标准。在需要直接盖髓的牙齿中，MTA治疗组和氢氧化钙治疗组的成功率之间存在统计学显著差异（P = 0.002）。对MTA与氢氧化钙用于直接盖髓的临床评估表明，在直接盖髓方面MTA优于氢氧化钙，失败率更低（风险差异0.1 [95%置信区间0.04至0.16]）。总之，与氢氧化钙相比，MTA用于直接盖髓具有更高的临床成功率，可能是氢氧化钙的合适替代品。
