State Key Laboratory of Crop Stress Biology for Arid Areas, College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi, China.
Int J Mol Sci. 2019 Jan 8;20(1):206. doi: 10.3390/ijms20010206.
Wheat and barley are the most highly produced and consumed grains in the world. Various pathogens-viruses, bacteria, fungi, insect pests, and nematode parasites-are major threats to yield and economic losses. Strategies for the management of disease control mainly depend on resistance or tolerance breeding, chemical control, and biological control. The discoveries of RNA silencing mechanisms provide a transgenic approach for disease management. Host-induced gene silencing (HIGS) employing RNA silencing mechanisms and, specifically, silencing the targets of invading pathogens, has been successfully applied in crop disease prevention. Here, we cover recent studies that indicate that HIGS is a valuable tool to protect wheat and barley from diseases in an environmentally friendly way.
小麦和大麦是世界上产量和消费量最高的谷物。各种病原体——病毒、细菌、真菌、虫害和线虫寄生虫——是对产量和经济损失的主要威胁。疾病控制管理策略主要取决于抗性或耐受性育种、化学控制和生物控制。RNA 沉默机制的发现为疾病管理提供了一种转基因方法。利用 RNA 沉默机制的宿主诱导基因沉默（HIGS），特别是沉默入侵病原体的靶标，已成功应用于作物病害防治。在这里，我们综述了最近的研究表明，HIGS 是一种环保的保护小麦和大麦免受疾病侵害的有价值的工具。
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