治疗与淋巴增生性疾病相关的难治性乳糜胸的经验。
Experiences in the treatment of refractory chylothorax associated with lymphoproliferative disorders.
机构信息
4th Department of Internal Medicine - Hematology, University Hospital, Sokolska Street 581, 5005, Hradec Kralove, Czech Republic.
Faculty of Medicine in Hradec Králové, Charles University Prague, Hradec Kralove, Czech Republic.
出版信息
Orphanet J Rare Dis. 2019 Jan 9;14(1):9. doi: 10.1186/s13023-018-0991-3.
BACKGROUND
Chylothorax is a rare condition which can be associated with malignant lymphoproliferative disorders (LPDs). We retrospectively analyzed the results of the conservative treatment of 10 patients with persistent non-traumatic malignant chylothorax.
RESULTS
Conservative treatment lead to a decline of chylothorax after mean of 66 days and consisted of the treatment of the underlying disease and of simultaneous long-term supportive care (drainage of the thoracic cavity, dietary measures and nutrition management). In most cases (80%), chylothorax disappeared only after a successful therapeutic response of the underlying disease. Low-dose radiotherapy had very good effects in two patients.
CONCLUSION
Conservative treatment of malignant chylothorax can be considered a suitable method. Based on our results, successful treatment of the lymphoproliferative disorder seems to be a very important factor for the disappearance of chylothorax.
背景
乳糜胸是一种罕见的病症，可能与恶性淋巴增生性疾病（LPD）有关。我们回顾性分析了 10 例持续性非创伤性恶性乳糜胸患者的保守治疗结果。
结果
保守治疗平均 66 天后导致乳糜胸减少，包括基础疾病的治疗和长期支持性护理（胸腔引流、饮食措施和营养管理）。在大多数情况下（80%），只有在基础疾病得到成功治疗后，乳糜胸才会消失。两名患者接受低剂量放疗效果非常好。
结论
恶性乳糜胸的保守治疗可以被认为是一种合适的方法。根据我们的结果，淋巴增生性疾病的成功治疗似乎是乳糜胸消失的一个非常重要的因素。
Zotero 插件