State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China.
University of Science and Technology of China, Hefei, 230026, Anhui, China.
Mikrochim Acta. 2019 Jan 9;186(2):74. doi: 10.1007/s00604-018-3183-x.
The authors report that CuO/NiO hollow nanocomposites are an effective bifunctional catalyst capable of oxidizing glucose and reducing hydrogen peroxide. Synthesis is based on a solvothermal process and subsequent thermal treatment. The structure can be controlled by adjusting the amounts of added NiCl during the solvothermal etching process, and core-shell, yolk-shell or hollow structures can be obtained. The porous hollow structure composite of type CuO/NiO was used to modify a glassy carbon electrode. It exhibits excellent electrocatalytic activity towards glucose oxidation in solution of pH 13, typically at a working potential of +0.60 V (vs. Ag/AgCl). This enables voltammetric sensing of glucose with (a) a low limit of detection (0.08 μM, at S/N = 3), (b) over a wide linear range (0.20 μM - 2.5 mM), and (c) high sensitivity (2043 μA·mM·cm). The sensor is reproducible, selective and stable. It can be used to detect glucose in spiked human serum. The CuO/NiO composite also displays good electrocatalytic activity towards reduction of HO in neutral aqueous medium, typically at an applied potential of -0.35 V. It has a detection limit of 90 nM, a sensitivity of 271.1 μA·mM·cm, and a linear detection range that extends from 0.30 μM to 9.0 mM. Graphical abstract CuO/NiO nanocomposites with three different structures were synthesized by coordinated etching precipitation method. The hollow structure CuO/NiO was coated on the surface of glassy carbon electrode for the amperometric determination of glucose and hydrogen peroxide.
作者报告称，CuO/NiO 空心纳米复合材料是一种有效的双功能催化剂，能够氧化葡萄糖并还原过氧化氢。合成基于溶剂热法和随后的热处理。通过调整溶剂热刻蚀过程中添加的 NiCl 的量，可以控制结构，并获得核壳、蛋黄壳或空心结构。CuO/NiO 型多孔空心结构复合材料被用于修饰玻碳电极。它在 pH 13 的溶液中对葡萄糖氧化表现出优异的电催化活性，通常在+0.60 V（相对于 Ag/AgCl）的工作电位下。这使得可以通过伏安法在低检测限（0.08 μM，S/N=3）下检测葡萄糖，具有宽线性范围（0.20 μM-2.5 mM）和高灵敏度（2043 μA·mM·cm）。传感器具有可重复性、选择性和稳定性。它可用于检测加标人血清中的葡萄糖。CuO/NiO 复合材料对中性水溶液中 HO 的还原也表现出良好的电催化活性，通常在施加的-0.35 V 下。它的检测限为 90 nM，灵敏度为 271.1 μA·mM·cm，线性检测范围从 0.30 μM 扩展到 9.0 mM。
